BIN1 Antikörper (AA 189-398)

Produktnummer ABIN1105531

Dieser Maus Monoklonal Antikörper detektiert spezifisch BIN1 in WB, IHC (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Schwein und Huhn.

Kurzübersicht für BIN1 Antikörper (AA 189-398) (ABIN1105531)

Target: BIN1 (Bridging Integrator 1 (BIN1))

Reaktivität: Human, Maus, Ratte, Schwein, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: BN-1

Produktdetails anti-BIN1 Antikörper

Bindungsspezifität: AA 189-398

Spezifität: Recognizes BIN1. No cross reactivity with other proteins.

Aufreinigung: Affinity Chromatography

Immunogen: Recombinant polypeptide containing amino acids 189-398 of Human Bin1.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1.2 % Sodium Acetate or neutral PBS.

Konzentration: 0.1 mg/mL

Buffer: 1.2 % Sodium Acetate containing 2 mg BSA and 0.01 mg Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BIN1

Target: BIN1 (Bridging Integrator 1 (BIN1))

Andere Bezeichnung: BIN1 / AMPHL

Hintergrund: BIN1 (AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei.Synonyms: Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, Myc box-dependent-interacting protein 1

Gen-ID: 274, 9606

UniProt: O00499