BIN1 Antikörper (AA 189-398)

Produktnummer ABIN1105531

Dieses Maus Monoklonal-Antikörper erkennt spezifisch BIN1 in WB, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Schwein und Huhn.

Kurzübersicht für BIN1 Antikörper (AA 189-398) (ABIN1105531)

Target: BIN1 (Bridging Integrator 1 (BIN1))

Reaktivität: Human, Maus, Ratte, Schwein, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: BN-1

Produktdetails anti-BIN1 Antikörper

Bindungsspezifität: AA 189-398

Spezifität: Recognizes BIN1. No cross reactivity with other proteins.

Aufreinigung: Affinity Chromatography

Immunogen: Recombinant polypeptide containing amino acids 189-398 of Human Bin1.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1.2 % Sodium Acetate or neutral PBS.

Konzentration: 0.1 mg/mL

Buffer: 1.2 % Sodium Acetate containing 2 mg BSA and 0.01 mg Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BIN1

Target: BIN1 (Bridging Integrator 1 (BIN1))

Andere Bezeichnung: BIN1 / AMPHL

Hintergrund: BIN1 (AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei.Synonyms: Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, Myc box-dependent-interacting protein 1

Gen-ID: 274, 9606

UniProt: O00499