BHLHE22 Antikörper (N-Term)

Produktnummer ABIN1105525

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BHLHE22 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh) und Huhn.

Kurzübersicht für BHLHE22 Antikörper (N-Term) (ABIN1105525)

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BHLHE22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BHLHE22 Antikörper

Bindungsspezifität: N-Term

Sequenz: LPAGAALCLK YGESASRGSV AESSGGEQSP DDDSDGRCEL VLRAGVADPR

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, ZebrafishSpecies reactivity (tested):Human

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-BHLHB5 antibody: synthetic peptide directed towards the N terminal of human BHLHB5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu BHLHE22

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Andere Bezeichnung: BHLHB5 / BHLHE22

Hintergrund: BHLHB5 is a member of family of basic helix-loop-helix (bHLH) transcription factors. Members of this family have been implicated in many aspects of neural development, including cell growth, differentiation, and cell migration. BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA.Synonyms: Class B basic helix-loop-helix protein 5, Class E basic helix-loop-helix protein 22, TNRC20, Trinucleotide repeat-containing gene 20 protein

Gen-ID: 27319

NCBI Accession: NP_689627