Stromal Cell Derived Factor Antikörper

Produktnummer ABIN110540

Der Kaninchen Polyklonal anti-Stromal Cell Derived Factor Antikörper wird verwendet zum Nachweis von Stromal Cell Derived Factor in Proben von Maus. Er wurde validiert für IP, IHC und WB.

Kurzübersicht für Stromal Cell Derived Factor Antikörper (ABIN110540)

Target: Stromal Cell Derived Factor

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Lagerung: 4 °C

Antigendetails

Target: Stromal Cell Derived Factor

Andere Bezeichnung: SDF-1 (Stromal Cell-Derived Factor, PBSF)

Hintergrund: SDF-1a (stromal cell-derived factor-a)1, also known as pre-B-cell growth-stimulating factor (PBSF)2, is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line1. Targeted deletion of SDF-1 gene resulted in defects ofB-cell lymphopoiesis and bone marrow myelopoiesis3. SDF-1 has been shown to be chemotactic for lymphocytes4. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells5,6., SDF-1 binding to CXCR4 inhibits HIV-1 entry5,6.