AGGF1 Antikörper

Produktnummer ABIN1105264

Produktdetails anti-AGGF1 Antikörper

Target: AGGF1 (Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGGF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: The antibody reacts with human VG5Q, a 84 kDa protein.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A

Immunogen: VG5Q functions as an angiogenic factor in promoting angiogenesis and suppression of VG5Q expression inhibits vessel formation. Angiogenic factors are critical to the initiation of angiogenesis and maintenance of the vascular network. Angiogenesis has an essential role in pathological conditions such as cancer and various ischaemic and inflammatory diseases. VG5Q can bind to endothelial cells and promote cell proliferation, suggesting that the protein may act in an autocrine fashion. VG5Q interacts with TWEAK (also known as TNFSF12), another secreted angiogenic factor. VG5Q shows strong expression in blood vessels and is secreted when vessel formation is initiated. VG5Q protein was detected mostly in the cytoplasm and around the nuclei of human microvascular endothelial cells (HMVECs). Furthermore VG5Q is detected in human umbilical vein endothelial cells (HUVECs), human heart fibroblast (HHF) and ovarian cancer cells (OV-3), but low expression was detected in kidney cancer cells (RP-45), HeLa Cells and bladder cancer cells.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu AGGF1

Target: AGGF1 (Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1))

Andere Bezeichnung: AGGF1 / VG5Q (AGGF1 Produkte)

Synonyme: RGD1310888 antikoerper, AGGF1 antikoerper, LOC100037685 antikoerper, im:7146636 antikoerper, zgc:152959 antikoerper, DKFZp459G1317 antikoerper, GPATC7 antikoerper, GPATCH7 antikoerper, HSU84971 antikoerper, HUS84971 antikoerper, VG5Q antikoerper, 2010009L17Rik antikoerper, 2310029P06Rik antikoerper, AW112072 antikoerper, Peg3 antikoerper, angiogenic factor with G patch and FHA domains 1 antikoerper, angiogenic factor with G-patch and FHA domains 1 antikoerper, Aggf1 antikoerper, AGGF1 antikoerper, aggf1 antikoerper, CC1G_06398 antikoerper

Hintergrund: Synonyms: Angiogenic factor VG5Q, Angiogenic factor with G patch and FHA domains 1, G patch domain-containing protein 7, GPATC7, GPATCH7, Vasculogenesis gene on 5q protein

Gen-ID: 55109

NCBI Accession: NP_060516

UniProt: Q8N302