ADAMTSL1 Antikörper (N-Term)

Produktnummer ABIN1105253

Der Maus Monoklonal Anti-ADAMTSL1-Antikörper wurde für WB und EIA validiert. Er ist geeignet, ADAMTSL1 in Proben von Human zu detektieren.

Kurzübersicht für ADAMTSL1 Antikörper (N-Term) (ABIN1105253)

Target: ADAMTSL1 (ADAMTS-Like 1 (ADAMTSL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ADAMTSL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: IBL-5-25

Produktdetails anti-ADAMTSL1 Antikörper

Bindungsspezifität: N-Term

Spezifität: Monoclonal antibody 1B2-8-2 reacts with Punctin-1 (ADAMTSL-1). It recognizes the first thrombospondin repeat near the N-terminal and reacts with molecular species of 55 kDa or a doublet of 55 k Da and 60 kDa (glycosylated form). Note that proteolysis of Punctin-1 has been described and additional smaller bands may also be obtained.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Protein G, 0.02 % sodium azide, 0.1 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu ADAMTSL1

Target: ADAMTSL1 (ADAMTS-Like 1 (ADAMTSL1))

Andere Bezeichnung: ADAMTSL1

Hintergrund: Punctin-1 is a secreted molecule resembling members of the family of proteases designated ADAMTS (a disintegrin-like and metalloprotease domain with thrombospondin type I motif). ADAMTS proteases are secreted enzymes that consist of a metalloprotease domain (which provides the catalytic activity) and ancillary domains (which provide substrate, cell or extracellular matrix activity). Punctin-1 lacks the pro-metalloprotease and the disintegrin-like domain typical of this family but contains other ADAMTS domains in precise order including 4 thrombospondin-I repeats. Punctin-1 is an extracellular matrix protein in tissues and deposited into the cell substratum and localized towards the periphery of transfected cells. Punctin-1 and Punctin-2 (ADAMTSL-3) are the first members of a novel family of ADAMTS-like proteins that appear to have important functions in the extracellular matrix.Synonyms: ADAMTS-like protein 1, ADAMTSL-1, ADAMTSR1

Gen-ID: 92949

NCBI Accession: NP_001035362

UniProt: Q8N6G6