CHRNA1 Antikörper (N-Term, Subunit alpha)

Produktnummer ABIN1105213

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CHRNA1 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für CHRNA1 Antikörper (N-Term, Subunit alpha) (ABIN1105213)

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CHRNA1 Antikörper

Bindungsspezifität: N-Term, Subunit alpha

Spezifität: Recognizes CHRNA1

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse and Rat.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of Human CHRNA1, identical to the related Rat and Mouse sequence

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with 0.2 mL of distilled water to yield a concentration of 0.5 mg/mL.

Konzentration: 0.5 mg/mL

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CHRNA1

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Andere Bezeichnung: Acetylcholine Receptor alpha Subunit

Hintergrund: CHRNA, also termed ACHRA, is mapped on 2q24-q32.This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. (1) The protein-coding sequence of the human alpha subu gene is divided into 9 exons that correspond to different structural and functional domains of the precursor molecule. (2)Synonyms: ACHRA, CHNRA, CHRNA1

Gen-ID: 1134

NCBI Accession: NP_001034612

UniProt: P02708

Pathways: Skeletal Muscle Fiber Development