VGlut3 Transporter (AA 546-588), (C-Term) Antikörper

Produktnummer ABIN1098207

Der Maus Monoklonal anti-VGlut3 Transporter Antikörper (Klon S34-34) (ABIN1098207) detektiert spezifisch VGlut3 Transporter in IHC, WB und IF/ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte.

Kurzübersicht für VGlut3 Transporter (AA 546-588), (C-Term) Antikörper (ABIN1098207)

Target: VGlut3 Transporter

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)

Klon: S34-34

Produktdetails

Bindungsspezifität: AA 546-588, C-Term

Verwendungszweck: Anti-VGlut3 Transporter Mouse Monoclonal Antibody

Spezifität: This antibody recognizes human, mouse, and rat VGlut3. It does not cross-react with VGlut1 or VGlut2.

Kreuzreaktivität: Human, Maus, Ratte

Kreuzreaktivität (Details): No cross Reactivity with Vglut1 and Vglut2

Aufreinigung: Purified by Protein G affinity chromatography.

Immunogen: Fusion protein corresponding to aa 546-588 (cytoplasmic C-terminus) of rat VGlut3 (accession no. NP_74947.1).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoblotting: use at 1-2 μg/mL. A band of ~65 kDa is detected.
Immunohistochemistry: use at 1-5 μg/mL.
These are recommended concentrations.
Enduser should determine optimal concentrations for their applications.
Positive control: CV-1 fibroblasts transfected with VGlut3.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: This product is stable for at least 1 year at -20°C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.

Antigendetails

Target: VGlut3 Transporter

Hintergrund: Vesicular glutamate transporter 3,Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. {PubMed:12097496, PubMed:12388773}.,The ATP-dependent, chloride-sensitive vesicular glutamate transporters include VGlut1, VGlut2, and VGlut3. VGlut3 is a multipass membrane protein restricted to synaptic vesicles of glutamatergic neurons. It is specifically expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord, and thalamus.,Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Membrane, Cell junction, synapse, synaptosome,VGluT3, Solute carrier family 17 member 8

UniProt: Q7TSF2