Surfactant Protein C Antikörper (AA 60-180)

Produktnummer ABIN1098147

Dieses Anti-Surfactant Protein C-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Surfactant Protein C in ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für Surfactant Protein C Antikörper (AA 60-180) (ABIN1098147)

Target: Surfactant Protein C (SFTPC)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Surfactant Protein C Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 5E6A9

Produktdetails anti-Surfactant Protein C Antikörper

Bindungsspezifität: AA 60-180

Verwendungszweck: SFTPC Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human SFTPC (AA: 60-180 ) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Surfactant Protein C Antikörper (ABIN1098147)

Zhong, Zhou, Ann, Minoo, Liu, Banfalvi, Krishnaveni, Dubourd, Demaio, Willis, Kim, duBois, Crandall, Beers, Borok: "Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein." in: American journal of respiratory cell and molecular biology, Vol. 45, Issue 3, pp. 498-509, (2011) (PubMed).

Wang, Bridges, Na, Xu, Weaver: "Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C." in: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33377-83, (2009) (PubMed).

Details zu Surfactant Protein C

Target: Surfactant Protein C (SFTPC)

Andere Bezeichnung: SFTPC

Hintergrund: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Molekulargewicht: 21 kDa

UniProt: P11686