PPY Antikörper (AA 1-95)

Produktnummer ABIN1098139

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PPY in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für PPY Antikörper (AA 1-95) (ABIN1098139)

Target: PPY (Pancreatic Polypeptide (PPY))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PPY Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Klon: 2G5D12

Produktdetails anti-PPY Antikörper

Bindungsspezifität: AA 1-95

Verwendungszweck: PPY Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human PPY (AA: 1-95) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-PPY Antikörper (ABIN1098139)

Banerjee, Onyuksel: "Human pancreatic polypeptide in a phospholipid-based micellar formulation." in: Pharmaceutical research, Vol. 29, Issue 6, pp. 1698-711, (2012) (PubMed).

Naessén, Carlström, Holst, Hellström, Hirschberg: "Women with bulimia nervosa exhibit attenuated secretion of glucagon-like peptide 1, pancreatic polypeptide, and insulin in response to a meal." in: The American journal of clinical nutrition, Vol. 94, Issue 4, pp. 967-72, (2011) (PubMed).

Details zu PPY

Target: PPY (Pancreatic Polypeptide (PPY))

Andere Bezeichnung: PPY

Hintergrund: This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products, the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.

Molekulargewicht: 10.4 kDa

Gen-ID: 5539

UniProt: P01298

Pathways: Feeding Behaviour