TRIP6 Antikörper (AA 107-291)

Produktnummer ABIN1098130

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TRIP6 in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für TRIP6 Antikörper (AA 107-291) (ABIN1098130)

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TRIP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Klon: 6H4

Produktdetails anti-TRIP6 Antikörper

Bindungsspezifität: AA 107-291

Verwendungszweck: TRIP6 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human TRIP6 (AA: 107-291) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-TRIP6 Antikörper (ABIN1098130)

Willier, Butt, Richter, Burdach, Grunewald: "Defining the role of TRIP6 in cell physiology and cancer." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 103, Issue 12, pp. 573-91, (2011) (PubMed).

Lai, Lin, Zheng, Benveniste, Lin: "The adaptor protein TRIP6 antagonizes Fas-induced apoptosis but promotes its effect on cell migration." in: Molecular and cellular biology, Vol. 30, Issue 23, pp. 5582-96, (2010) (PubMed).

Details zu TRIP6

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Andere Bezeichnung: TRIP6

Hintergrund: This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.

Molekulargewicht: 50.3 kDa

UniProt: Q15654

Pathways: Cell-Cell Junction Organization