NEFH Antikörper (AA 968-1020)
Kurzübersicht für NEFH Antikörper (AA 968-1020) (ABIN1098127)
Target
Alle NEFH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 968-1020
-
Verwendungszweck
- NEFH Antibody
-
Aufreinigung
- Purified antibody
-
Immunogen
- Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. Coli.
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
- ELISA: 1/10000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." in: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).
: "Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign." in: Neurochemical research, Vol. 36, Issue 12, pp. 2287-91, (2011) (PubMed).
-
: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." in: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).
-
- NEFH (Neurofilament, Heavy Polypeptide (NEFH))
-
Andere Bezeichnung
- NEFH
-
Hintergrund
-
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
-
Molekulargewicht
- 112.4 kDa
-
Gen-ID
- 4744
-
UniProt
- P12036
Target
-