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NEFH Antikörper (AA 968-1020)

NEFH Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 8H10 unconjugated
Produktnummer ABIN1098127
  • Target Alle NEFH Antikörper anzeigen
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    Bindungsspezifität
    • 15
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 968-1020
    Reaktivität
    • 107
    • 77
    • 61
    • 47
    • 29
    • 23
    • 12
    • 12
    • 9
    • 9
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 65
    • 53
    • 7
    Maus
    Klonalität
    • 80
    • 45
    Monoklonal
    Konjugat
    • 77
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NEFH Antikörper ist unkonjugiert
    Applikation
    • 77
    • 40
    • 37
    • 26
    • 22
    • 20
    • 18
    • 13
    • 13
    • 12
    • 11
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Verwendungszweck
    NEFH Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. Coli.
    Klon
    8H10
    Isotyp
    IgG1
    Top Product
    Discover our top product NEFH Primärantikörper
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Singh, Yan, Hull, Read, OSullivan, Henderson, Rose, Greer, McCombe: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." in: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).

    Sellner, Patel, Dassan, Brown, Petzold: "Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign." in: Neurochemical research, Vol. 36, Issue 12, pp. 2287-91, (2011) (PubMed).

  • Target
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    Andere Bezeichnung
    NEFH (NEFH Produkte)
    Hintergrund
    Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

    Molekulargewicht
    112.4 kDa
    Gen-ID
    4744
    UniProt
    P12036
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