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ILK Antikörper (AA 97-244)

ILK Reaktivität: Human, Maus, Affe WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 3A9 unconjugated
Produktnummer ABIN1098122
  • Target Alle ILK Antikörper anzeigen
    ILK (Integrin-Linked Kinase (ILK))
    Bindungsspezifität
    • 26
    • 19
    • 15
    • 11
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 97-244
    Reaktivität
    • 109
    • 60
    • 54
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Affe
    Wirt
    • 118
    • 5
    • 1
    Maus
    Klonalität
    • 117
    • 7
    Monoklonal
    Konjugat
    • 63
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ILK Antikörper ist unkonjugiert
    Applikation
    • 91
    • 47
    • 40
    • 39
    • 24
    • 20
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Verwendungszweck
    ILK Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human ILK (AA: 97-244) expressed in E. Coli.
    Klon
    3A9
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Taylor, Qiao, Colon, Schlegel, Josifi, Chung: "Integrin-linked kinase regulates phosphatase and tensin homologue activity to promote tumorigenesis in neuroblastoma cells." in: Surgery, Vol. 150, Issue 2, pp. 162-8, (2011) (PubMed).

    Matsui, Assi, Ogawa, Raven, Dedhar, Gleave, Salh, So: "The importance of integrin-linked kinase in the regulation of bladder cancer invasion." in: International journal of cancer. Journal international du cancer, Vol. 130, Issue 3, pp. 521-31, (2011) (PubMed).

  • Target
    ILK (Integrin-Linked Kinase (ILK))
    Andere Bezeichnung
    ILK (ILK Produkte)
    Hintergrund
    Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
    Molekulargewicht
    51.4 kDa
    Gen-ID
    3611
    UniProt
    Q13418
    Pathways
    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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