CD6 Antikörper (AA 472-668)
Kurzübersicht für CD6 Antikörper (AA 472-668) (ABIN1098118)
Target
Alle CD6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 472-668
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Verwendungszweck
- CD6 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CD6 (AA: 472-668) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Aberrant expression of CD6 on B-cell subsets from patients with Sjögren's syndrome." in: Journal of autoimmunity, Vol. 35, Issue 4, pp. 336-41, (2010) (PubMed).
: "CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 28, pp. 11724-9, (2007) (PubMed).
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: "Aberrant expression of CD6 on B-cell subsets from patients with Sjögren's syndrome." in: Journal of autoimmunity, Vol. 35, Issue 4, pp. 336-41, (2010) (PubMed).
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- CD6
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Andere Bezeichnung
- CD6
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Hintergrund
- This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
- 71.8 kDa
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Gen-ID
- 923
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UniProt
- P30203
Target
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