Annexin a1 Antikörper (AA 144-248)

Produktnummer ABIN1098115

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Annexin a1 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Affe und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für Annexin a1 Antikörper (AA 144-248) (ABIN1098115)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reaktivität: Human, Maus, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Annexin a1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 2F1

Produktdetails anti-Annexin a1 Antikörper

Bindungsspezifität: AA 144-248

Verwendungszweck: ANXA1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human ANXA1 (AA: 144-248 ) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Annexin a1 Antikörper (ABIN1098115)

Nair, Hande, Lim: "Annexin-1 protects MCF7 breast cancer cells against heat-induced growth arrest and DNA damage." in: Cancer letters, Vol. 294, Issue 1, pp. 111-7, (2010) (PubMed).

Li, Shen, Huang, Huang, Wang, Wu: "Annexin-I overexpression is associated with tumour progression and independently predicts inferior disease-specific and metastasis-free survival in urinary bladder urothelial carcinoma." in: Pathology, Vol. 42, Issue 1, pp. 43-9, (2009) (PubMed).

Details zu Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Andere Bezeichnung: ANXA1

Hintergrund: Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

Molekulargewicht: 38.7 kDa

UniProt: P04083

Pathways: Hormone Transport