HNRNPA1 Antikörper

Produktnummer ABIN108609

Dieses Anti-HNRNPA1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von HNRNPA1 in WB, ELISA, IF, IP, ICC, IHC (p) und FACS. Geeignet für Human und Maus. Dieses Primary Antibody wurde in 10+ Publikationen zitiert.

Kurzübersicht für HNRNPA1 Antikörper (ABIN108609)

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HNRNPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: 9H10

Produktdetails anti-HNRNPA1 Antikörper

Aufreinigung: Protein A

Immunogen: Full length hnRNP-A1 native protein (partially purified) from HeLa cells (human)

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal antibody dilution should be determined by titration, however as a guideline try,Flow Cyt: Use 1 μg for 106 cells.IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval before commencing with IHC staining protocolWB: Use at 1:2000-1:4000. Detects a band of approximately 34 kDa (predicted molecular weight: 38 kDa)IP: Use at an assay dependent dilution. This antibody does not IP the hnRNP complex

Kommentare:

Myeloma, fusion partners: Balb/c Sp2/0 cell line

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-HNRNPA1 Antikörper (ABIN108609)

Woolley, Algie, Samuel, Harfoot, Wiles, Hung, Tan, Hains, Valova, Huschtscha, Royds, Perez, Yoon, Cohen, Robinson, Bay, Lasham, Braithwaite: "Prognostic association of YB-1 expression in breast cancers: a matter of antibody." in: PLoS ONE, Vol. 6, Issue 6, pp. e20603, (2011) (PubMed).

Beauchamp, Nassif, Hillock, van der Giessen, von Roretz, Jasmin, Gallouzi: "The cleavage of HuR interferes with its transportin-2-mediated nuclear import and promotes muscle fiber formation." in: Cell death and differentiation, Vol. 17, Issue 10, pp. 1588-99, (2010) (PubMed).

Read, Digard: "Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export." in: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1290-301, (2010) (PubMed).

Rosenberger, De-Castro Arce, Langbein, Steenbergen, Rösl: "Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 7006-11, (2010) (PubMed).

Sellier, Rau, Liu, Tassone, Hukema, Gattoni, Schneider, Richard, Willemsen, Elliott, Hagerman, Charlet-Berguerand: "Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients." in: The EMBO journal, Vol. 29, Issue 7, pp. 1248-61, (2010) (PubMed).

Kocgozlu, Lavalle, Koenig, Senger, Haikel, Schaaf, Voegel, Tenenbaum, Vautier: "Selective and uncoupled role of substrate elasticity in the regulation of replication and transcription in epithelial cells." in: Journal of cell science, Vol. 123, Issue Pt 1, pp. 29-39, (2009) (PubMed).

Lieberthal, Kaminsky, Parkhurst, Tanese: "The role of YY1 in reduced HP1alpha gene expression in invasive human breast cancer cells." in: Breast cancer research : BCR, Vol. 11, Issue 3, pp. R42, (2009) (PubMed).

Kashima, Rao, David, Manley: "hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing." in: Human molecular genetics, Vol. 16, Issue 24, pp. 3149-59, (2007) (PubMed).

van der Giessen, Gallouzi: "Involvement of transportin 2-mediated HuR import in muscle cell differentiation." in: Molecular biology of the cell, Vol. 18, Issue 7, pp. 2619-29, (2007) (PubMed).

Burd, Dreyfuss: "RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing." in: The EMBO journal, Vol. 13, Issue 5, pp. 1197-204, (1994) (PubMed).

Details zu HNRNPA1

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Andere Bezeichnung: hnRNP A1 

Hintergrund: Synonyms:
HNRNPA 1 antibody,Helix destabilizing protein antibody,Helix-destabilizing proteinantibody,Heterogeneous nuclear ribonucleoprotein A1 antibody,Heterogeneous nuclear ribonucleoprotein A1B proteinantibody,Heterogeneous nuclear ribonucleoprotein B2 protein antibody,Heterogeneous nuclear ribonucleoprotein coreprotein A1 antibody,hnRNP A1 antibody,hnRNP core protein A1 antibody,HNRNPA1 antibody,HNRPA1antibody,MGC102835 antibody,Nuclear ribonucleoprotein particle A1 protein antibody,ROA1_HUMANantibody

Gen-ID: 3178, 15382

OMIM: 164017

UniProt: P09651, P49312