FMR1 Antikörper (C-Term)

Produktnummer ABIN108598

Dieses Maus Monoklonal-Antikörper erkennt spezifisch FMR1 in WB, ELISA, IF, IP und ICC. Er zeigt eine Reaktivität gegenüber Drosophila melanogaster und wurde in 7+ Publikationen erwähnt.

Kurzübersicht für FMR1 Antikörper (C-Term) (ABIN108598)

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reaktivität: Drosophila melanogaster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FMR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: 6A15

Produktdetails anti-FMR1 Antikörper

Bindungsspezifität: C-Term

Keine Kreuzreaktivität: Human

Kreuzreaktivität (Details): Fruit fly (Drosophila melanogaster) Does not react with Human

Aufreinigung: Protein A

Immunogen: His-dFMR1 fusion protein (Drosophilia melanogaster) (C-terminal 580aa).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal antibody dilution should be determined by titration, however as a guideline try at IP: Use at 25 μg/mg of lysate WB: Use at an assay dependent dilution. Detects a band of approximately 85 kDa (predicted molecular weight: 82 kDa)

Kommentare:

Myeloma, fusion partners: SP2/0

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-FMR1 Antikörper (ABIN108598)

Callan, Clements, Ahrendt, Zarnescu: "Fragile X Protein is required for inhibition of insulin signaling and regulates glial-dependent neuroblast reactivation in the developing brain." in: Brain research, Vol. 1462, pp. 151-61, (2012) (PubMed).

Lim, Lee, Choi, Kilman, Kim, Park, Jang, Allada, Choe: "The novel gene twenty-four defines a critical translational step in the Drosophila clock." in: Nature, Vol. 470, Issue 7334, pp. 399-403, (2011) (PubMed).

Monzo, Dowd, Minden, Sisson: "Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila." in: Developmental biology, Vol. 340, Issue 2, pp. 408-18, (2010) (PubMed).

Callan, Cabernard, Heck, Luois, Doe, Zarnescu: "Fragile X protein controls neural stem cell proliferation in the Drosophila brain." in: Human molecular genetics, Vol. 19, Issue 15, pp. 3068-79, (2010) (PubMed).

Kwak, Drier, Barbee, Ramaswami, Yin, Wickens: "GLD2 poly(A) polymerase is required for long-term memory." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 38, pp. 14644-9, (2008) (PubMed).

Monzo, Papoulas, Cantin, Wang, Yates, Sisson: "Fragile X mental retardation protein controls trailer hitch expression and cleavage furrow formation in Drosophila embryos." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 48, pp. 18160-5, (2006) (PubMed).

Wan, Dockendorff, Jongens, Dreyfuss: "Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein." in: Molecular and cellular biology, Vol. 20, Issue 22, pp. 8536-47, (2000) (PubMed).

Details zu FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Andere Bezeichnung: Drosophila FMR1

Hintergrund: Synonyms:
Drosophila FMR1 antibody,dFMR antibody,dFMR1 antibody,dFXR antibody,Drosophila fragile X mentalretardation protein antibody,FMRP antibody,Fragile X mental retardation 1 antibody,Fragile X mental retardation1 protein antibody,fragile X mental retardation protein antibody,FRAXA antibody,Protein FMR1antibody

Gen-ID: 37528, 23879

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development