HNRNPL Antikörper

Produktnummer ABIN108588

Dieser Anti-HNRNPL Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von HNRNPL in WB, ELISA, IF, IHC (p), IP, FACS, ICC und IHC (fro). Geeignet für Human, Maus, Ratte und Molch. Dieses Primary Antibody wurde in 9+ Publikationen zitiert.

Kurzübersicht für HNRNPL Antikörper (ABIN108588)

Target: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Reaktivität: Human, Maus, Ratte, Molch

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HNRNPL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 4D11

Produktdetails anti-HNRNPL Antikörper

Aufreinigung: Protein A

Immunogen: Human hnRNP proteins (from HeLa cells) purified by affinity chromatography on ssDNA agarose

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal antibody dilution should be determined by titration, however as a guideline try, IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.WB: 1/2000. Detects a band of approximately 64 kDa (predicted molecular weight: 64 kDa).Flow Cyt: Use 1 μg for 106 cells.

Kommentare:

Myeloma, fusion partners: SP2/0

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-HNRNPL Antikörper (ABIN108588)

Peddigari, Li, Rabe, Martin: "hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition." in: Nucleic acids research, Vol. 41, Issue 1, pp. 575-85, (2012) (PubMed).

Motta-Mena, Smith, Mallory, Jackson, Wang, Lynch: "A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs)." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 20043-53, (2011) (PubMed).

Heyd, Lynch: "Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing." in: Molecular cell, Vol. 40, Issue 1, pp. 126-37, (2010) (PubMed).

Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

Niu, Terasaki, Komatsu, Noguchi, Shichijo, Itoh: "Identification of peptides applicable as vaccines for HLA-A26-positive cancer patients." in: Cancer science, Vol. 100, Issue 11, pp. 2167-74, (2009) (PubMed).

Jia, Liu, Tao, Kruhlak, Guo, Meyers, Baker, Zheng: "Control of the papillomavirus early-to-late switch by differentially expressed SRp20." in: Journal of virology, Vol. 83, Issue 1, pp. 167-80, (2008) (PubMed).

Venables, Koh, Froehlich, Lapointe, Couture, Inkel, Bramard, Paquet, Watier, Durand, Lucier, Gervais-Bird, Tremblay, Prinos, Klinck, Elela, Chabot: "Multiple and specific mRNA processing targets for the major human hnRNP proteins." in: Molecular and cellular biology, Vol. 28, Issue 19, pp. 6033-43, (2008) (PubMed).

Rothrock, House, Lynch: "HnRNP L represses exon splicing via a regulated exonic splicing silencer." in: The EMBO journal, Vol. 24, Issue 15, pp. 2792-802, (2005) (PubMed).

Piñol-Roma, Swanson, Gall, Dreyfuss: "A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts." in: The Journal of cell biology, Vol. 109, Issue 6 Pt 1, pp. 2575-87, (1990) (PubMed).

Details zu HNRNPL

Target: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Andere Bezeichnung: hnRNP L

Hintergrund: Synonyms:
D830027H13Rik antibody,FLJ35509 antibody,Heterogeneous nuclear ribonucleoprotein L antibody,hnRNPLantibody,hnRPL antibody,P/OKcl.14 antibody

Gen-ID: 3191, 15388, 80846

OMIM: 603083

UniProt: P31943