SMN1 Antikörper

Produktnummer ABIN108566

Der Maus Monoklonal Anti-SMN1-Antikörper wurde für WB, ELISA, IF, IP, ICC, IHC (p) und FACS validiert. Er ist geeignet, SMN1 in Proben von Human, Maus und Xenopus laevis zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für SMN1 Antikörper (ABIN108566)

Target: SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

Reaktivität: Human, Maus, Xenopus laevis

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SMN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: 2B1

Produktdetails anti-SMN1 Antikörper

Aufreinigung: Protein A

Immunogen: Purified recombinant His 6 tagged-SMN protein (human)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal antibody dilution should be determined by titration, however as a guideline try at IHC-P: Use a concentration of 5 μg/mL. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocolWB: Use at an assay dependent dilution. Detects a band of approximately 42 kDa (predicted molecular weight: 35 kDa)Flow Cyt: Use 1 μg for 106 cells.

Kommentare:

Myeloma, fusion partners: A/J Sp2/0 cell line,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-SMN1 Antikörper (ABIN108566)

Grondard, Biondi, Armand, Lécolle, Della Gaspera, Pariset, Li, Gallien, Vidal, Chanoine, Charbonnier: "Regular exercise prolongs survival in a type 2 spinal muscular atrophy model mouse." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 25, Issue 33, pp. 7615-22, (2005) (PubMed).

Liu, Dreyfuss: "A novel nuclear structure containing the survival of motor neurons protein." in: The EMBO journal, Vol. 15, Issue 14, pp. 3555-65, (1996) (PubMed).

Details zu SMN1

Target: SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

Andere Bezeichnung: Gemin 1

Hintergrund: Synonyms:
BCD541 antibody,Gemin 1 antibody,Gemin-1 antibody,Gemin1 antibody,OTTHUMP00000125198antibody,OTTHUMP00000223567 antibody,OTTHUMP00000223568 antibody,OTTHUMP00000224066antibody,OTTHUMP00000226924 antibody,SMA 1 antibody,SMA 2 antibody,SMA 3 antibody,SMA 4 antibody,SMAantibody,SMA@ antibody,SMA1 antibody,SMA2 antibody,SMA3 antibody,SMA4 antibody,SMN 1 antibody,SMNantibody,SMN-1 antibody,SMN1 antibody,SMNT antibody,Survival motor neuron protein antibody,Survival ofmotor neuron 1 (telomeric) antibody,survival of motor neuron 1 antibody,Survival of motor neuron 1, telomericantibody,T-BCD541 antibody

Gen-ID: 6606, 6607, 20595

OMIM: 600354

UniProt: Q16637, P97801

Pathways: Ribonucleoprotein Complex Subunit Organization