Cellular Fibronectin Antikörper

Produktnummer ABIN108413

Der Maus Monoklonal Anti-Cellular Fibronectin-Antikörper wurde für IHC, WB und ELISA validiert. Er ist geeignet, Cellular Fibronectin in Proben von Human, Huhn, Meerschweinchen, Kaninchen und Ratte zu detektieren.

Kurzübersicht für Cellular Fibronectin Antikörper (ABIN108413)

Target: Cellular Fibronectin (Fibronectin, Cellular)

Reaktivität: Human, Huhn, Meerschweinchen, Kaninchen, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cellular Fibronectin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Klon: DH1

Produktdetails anti-Cellular Fibronectin Antikörper

Spezifität: The antibody is specific to extradomain A (EDA) sequence of a cellular fibronectin and recognizes thus only the cellular fibronectin. Mab DHI has been shown to specifically block chondrocyte condensation in chicken embryos (5). The antibody crossreacts with human, chicken, rat, rabbit and guinea pig

Immunogen: Monoclonal antibody (Mab) to cFn is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Purified fibronectin from A8387 fibrosarcoma cells was used as an immunogen (21).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: No reactivity with paraffin sections. Working dilution in western blotting is at least 1:1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Details zu Cellular Fibronectin

Target: Cellular Fibronectin (Fibronectin, Cellular)

Andere Bezeichnung: Cellular Fibronectin (cFn)

Hintergrund: The monoclonal antibody DH1 recognizes only cellular form of Fibronectin. DH1 is specific to the extra domain A (EDA) of the molecule. cFns are found in some basement membranes during development and only in distinct tissues in adult, for instance in smooth muscle and alveolar walls of airways. cFns are abundant in the plasma of carcinoma patients and in the stroma of various carcinomas.