LMAN1 Antikörper (C-Term)

Produktnummer ABIN1077459

Dieses Anti-LMAN1-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von LMAN1 in WB und ELISA. Geeignet für Human und Maus.

Kurzübersicht für LMAN1 Antikörper (C-Term) (ABIN1077459)

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser LMAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 1H6D8G7

Produktdetails anti-LMAN1 Antikörper

Bindungsspezifität: C-Term

Spezifität: At least two isoforms of ERGIC53 are known to exist.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Mouse monoclonal ERGIC53 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ERGIC53.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ERGIC53 antibody can be used for detection of ERGIC53 by Western blot at 1 - 2 μg/mL.

Kommentare:

(CT) Endoplasmic reticulum-golgi intermediate compartment protein 53

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C

Informationen zur Lagerung: ERGIC53 Monoclonal antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu LMAN1

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Andere Bezeichnung: LMAN1

Hintergrund: ERGIC53, also known as lectin mannose-binding 1 (LMAN1) protein is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
Synonyms: Lectin mannose-binding 1, LMAN1, endoplasmic reticulum-golgi intermediate compartment protein 53, ERGIC-53, F5F8D, FMFD1, MCFD1, MR60, gp58

Molekulargewicht: 56 kDa (calculated)

Gen-ID: 3998

NCBI Accession: NP_005561