FOXP3 Antikörper (C-Term)
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- Target Alle FOXP3 Antikörper anzeigen
- FOXP3 (Forkhead Box P3 (FOXP3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser FOXP3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3.
- Isotyp
- IgG
- Top Product
- Discover our top product FOXP3 Primärantikörper
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- Applikationshinweise
- FOXP3 antibody can be used for detection of FOXP3 by Western blot at 1 - 2 μg/mL.
- Kommentare
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(CT) Forkhead box P3
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- FOXP3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Haltbarkeit
- 12 months
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- Target
- FOXP3 (Forkhead Box P3 (FOXP3))
- Andere Bezeichnung
- FOXP3 (FOXP3 Produkte)
- Synonyme
- foxp3 antikoerper, FOXP3 antikoerper, AIID antikoerper, DIETER antikoerper, IPEX antikoerper, PIDX antikoerper, XPID antikoerper, JM2 antikoerper, scurfin antikoerper, sf antikoerper, RGD1562112 antikoerper, forkhead box P3 antikoerper, forkhead box P3a antikoerper, forkhead box P3 L homeolog antikoerper, FOXP3 antikoerper, foxp3a antikoerper, foxp3 antikoerper, foxp3.L antikoerper, Foxp3 antikoerper
- Hintergrund
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FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
Synonyms: Forkhead box P3, JM2, AIID, IPEX, PIDX, XPID, DIETER, scurfin - Molekulargewicht
- 47 kDa (calculated)
- Gen-ID
- 50943
- NCBI Accession
- NP_054728
- Pathways
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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