FOXP3 Antikörper (C-Term)

Produktnummer ABIN1077427

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch FOXP3 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für FOXP3 Antikörper (C-Term) (ABIN1077427)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser FOXP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-FOXP3 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FOXP3 antibody can be used for detection of FOXP3 by Western blot at 1 - 2 μg/mL.

Kommentare:

(CT) Forkhead box P3

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C

Informationen zur Lagerung: FOXP3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Andere Bezeichnung: FOXP3

Hintergrund: FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
Synonyms: Forkhead box P3, JM2, AIID, IPEX, PIDX, XPID, DIETER, scurfin

Molekulargewicht: 47 kDa (calculated)

Gen-ID: 50943

NCBI Accession: NP_054728

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation