SHROOM1 Antikörper (C-Term)

Produktnummer ABIN1077406

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SHROOM1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für SHROOM1 Antikörper (C-Term) (ABIN1077406)

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHROOM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SHROOM1 Antikörper

Bindungsspezifität: C-Term

Spezifität: SHROOM1 antibody is human, mouse and rat reactive. At least three isoforms of SHROOM1 are known to exist, this antibody will detect only the two largest isoforms. SHROOM1 antibody is predicted to not cross-react with other SHROOM family members.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal SHROOM1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SHROOM1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SHROOM1 antibody can be used for detection of SHROOM1 by Western blot at 1 - 2 μg/mL.

Kommentare:

(CT) SHROOM family member 1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C

Informationen zur Lagerung: SHROOM1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu SHROOM1

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Andere Bezeichnung: SHROOM1

Hintergrund: SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.
Synonyms: SHROOM family member 1, Shroom, apical protein 2, APXL2

Molekulargewicht: 94 kDa

Gen-ID: 134549

NCBI Accession: NP_001166171