TDGF1 Antikörper (N-Term)

Produktnummer ABIN1077401

Produktdetails anti-TDGF1 Antikörper

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TDGF1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal TDGF1 antibody was raised against a 17 amino acid peptide near the amino terminus of human TDGF1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TDGF1 antibody can be used for detection of TDGF1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Kommentare:

(NT) Teratocarcinomaderived growth factor 1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C

Informationen zur Lagerung: TDGF1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu TDGF1

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Andere Bezeichnung: TDGF1 (TDGF1 Produkte)

Hintergrund: Teratocarcinoma-derived growth factor 1 (TDGF1 or Cripto) is a member of the epidermal growth factor-cripto FRL1 cryptic protein family and is involved in the activation of several different signaling pathways during embryonic development and cellular transformation. It is first expressed in the forming mesoderm during gastrulation but later in development the expression is restricted to the truncus arteriosus of the developing heart. This suggests that TDGF1 mediates the progression of epiblastic cells that give rise to the mesoderm. TDGF1 overexpression is characteristic of human gastric and colorectal carcinomas.
Synonyms: Teratocarcinomaderived growth factor 1, Epidermal growth factor-like cripto protein CR1, Cripto-1 growth factor, CRGF, CR, CRGF, CRIPTO, Cripto-1

Molekulargewicht: 21 kDa

Gen-ID: 6997

NCBI Accession: NP_003203

Pathways: EGFR Signaling Pathway