CMPK2 Antikörper (C-Term)

Produktnummer ABIN1077386

Der Kaninchen Polyklonal anti-CMPK2 Antikörper wird verwendet zum Nachweis von CMPK2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA und IF.

Kurzübersicht für CMPK2 Antikörper (C-Term) (ABIN1077386)

Target: CMPK2 (Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CMPK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-CMPK2 Antikörper

Bindungsspezifität: C-Term

Spezifität: Multiple isoforms of CMPK2 are known to exist.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: CMPK2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human CMPK2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CMPK2 antibody can be used for detection of CMPK2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.

Kommentare:

(CT) Cytidine monophosphate (UMP-CMP) kinase 2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C

Informationen zur Lagerung: CMPK2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu CMPK2

Target: CMPK2 (Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2))

Andere Bezeichnung: CMPK2

Hintergrund: UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response
Synonyms: Cytidine monophosphate (UMP-CMP) kinase 2, TMPK2, TYKi, UMP-CMPK2

Molekulargewicht: 49 kDa

Gen-ID: 129607

NCBI Accession: NP_997198

Pathways: Nucleotide Phosphorylation, Cellular Response to Molecule of Bacterial Origin