SNCA Antikörper (Internal Region)

Produktnummer ABIN1049515

Dieser Ziege Polyklonal Antikörper detektiert spezifisch SNCA in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für SNCA Antikörper (Internal Region) (ABIN1049515)

Target: SNCA (Synuclein, alpha (SNCA))

Reaktivität: Human, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SNCA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Güteklasse: Verified

Produktdetails anti-SNCA Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Alpha-synuclein

Sequenz: ATGFVKKDQL GK

Spezifität: This antibody is expected to recognize both reported isoforms (NP_009292.1, NP_000336.1). Reported variants represent identical protein: NP_000336.1, NP_001139527.1, NP_001139526.1

Kreuzreaktivität: Hund, Human, Maus, Schwein, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-ATGFVKKDQLGK, from the of the protein sequence according to NP_009292.1, NP_000336.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: Paraffin embedded Human Brain (Cerebellum). Recommended concentration: 5 μg/mL.

Western Blot: Approx 17 kDa band observed in Human Brain (Amygdala) and fetal Mouse Brain lysates (calculated MW of 14.5 kDa according to Human NP_000336.1 and Mouse NP_033247.1). This molecular weight is routinely observed by other sources. Recommended co

Peptide ELISA: antibody detection limit dilution 1:128000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Details zu SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Andere Bezeichnung: SNCA

Hintergrund: SNCA, synuclein, alpha (non A4 component of amyloid precursor), NACP, PARK1, PARK4, PD1, alpha-synuclein, non A-beta component of AD amyloid, synuclein alpha-140

Gen-ID: 6622, 20617, 29219

NCBI Accession: NP_009292, NP_000336

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity