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CCL20 Antikörper

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch CCL20 in WB. Er zeigt eine Reaktivität gegenüber Maus und wurde in 1 Publikation erwähnt.
Rockland
Produktnummer ABIN1043833
Hersteller Produkt- Nr.: 210-501-b51

Kurzübersicht für CCL20 Antikörper (ABIN1043833)

Target

Alle CCL20 Antikörper anzeigen
CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Reaktivität

  • 80
  • 40
  • 15
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Maus

Wirt

  • 63
  • 38
  • 3
  • 1
  • 1
Ratte

Klonalität

  • 64
  • 42
Monoklonal

Konjugat

  • 58
  • 13
  • 7
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CCL20 Antikörper ist unkonjugiert

Applikation

  • 74
  • 49
  • 38
  • 34
  • 26
  • 13
  • 13
  • 10
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Klon

4N5F7
  • Hersteller Produkt- Nr.

    210-501-b51

    Hersteller

    Rockland

    Verwendungszweck

    MIP-3 alpha Antibody

    Kreuzreaktivität (Details)

    This antibody is specific for mouse MIP-3α protein.

    Produktmerkmale

    Synonyms: rat anti-MIP-3α antibody, CCL20, C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1

    Aufreinigung

    This product was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above.

    Sterilität

    Sterile filtered

    Immunogen

    Immunogen: Anti-MIP-3alpha (RAT) Monoclonal Antibody was produced in rat by repeated immunizations with mature full length recombinant mouse MIP-3alpha produced in E.coli followed by hybridoma development.

    Immunogen Type: Recombinant Protein

    Isotyp

    IgG
  • Applikationshinweise

    Application Note: MIP-3α antibody has been tested for use in western blot and suitable for ELISA, IP, and Neutralization. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 0.5 μg/mL

    Other: User Optimized

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.0 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • Lisignoli, Manferdini, Codeluppi, Piacentini, Grassi, Cattini, Filardo, Facchini: "CCL20/CCR6 chemokine/receptor expression in bone tissue from osteoarthritis and rheumatoid arthritis patients: different response of osteoblasts in the two groups." in: Journal of cellular physiology, Vol. 221, Issue 1, pp. 154-60, (2009) (PubMed).

  • Target

    CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

    Andere Bezeichnung

    Ccl20

    Hintergrund

    Background: MIP-3α (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3α inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3α also possesses antibacterial activity against E.coli and S.aureus. MIP-3α is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.

    Gen-ID

    20297

    NCBI Accession

    NP_001153210

    UniProt

    O89093

    Pathways

    Phosphorylierungen bei SARS-CoV-2 Infektion
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