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Interleukin 17a Antikörper

IL17A Reaktivität: Human WB, FACS Wirt: Maus Monoclonal 4H1524-1 unconjugated
Produktnummer ABIN1043781
  • Target Alle Interleukin 17a (IL17A) Antikörper anzeigen
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    Reaktivität
    • 102
    • 54
    • 19
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    Human
    Wirt
    • 62
    • 51
    • 29
    • 8
    • 3
    Maus
    Klonalität
    • 80
    • 72
    • 1
    Monoklonal
    Konjugat
    • 68
    • 24
    • 15
    • 11
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Interleukin 17a Antikörper ist unkonjugiert
    Applikation
    • 74
    • 63
    • 48
    • 15
    • 12
    • 12
    • 12
    • 11
    • 10
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Spezifität
    Anti-Human IL-17A (MOUSE) Monoclonal Antibody was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for human IL-17A protein. A BLAST analysis was used to suggest cross-reactivity with IL-17A from human sources based on 100% homology with the immunizing sequence. Cross-reactivity with IL-17A from other sources has not been determined.
    Produktmerkmale
    IL17-A (also known as Interleukin-17) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC. Anti-IL-17A antibody is ideal for investigators involved in Immunology research.
    Sterilität
    Sterile filtered
    Immunogen
    Anti-IL-17A (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17A produced in E.coli followed by hybridoma development.
    Immunogen Type: RecombinantProtein
    Klon
    4H1524-1
    Isotyp
    IgG2b
    Top Product
    Discover our top product IL17A Primärantikörper
  • Applikationshinweise
    Anti-Human IL-17A antibody has been tested for use in FLOW and Western Blot. Specific conditions for reactivity should be optimized by the end user.
    Kommentare

    Gene Name: IL17A

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Haltbarkeit
    12 months
  • Paust, Turner, Steinmetz, Peters, Heymann, Hölscher, Wolf, Kurts, Mittrücker, Stahl, Panzer: "The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis." in: Journal of the American Society of Nephrology : JASN, Vol. 20, Issue 5, pp. 969-79, (2009) (PubMed).

  • Target
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    Andere Bezeichnung
    IL-17A (IL17A Produkte)
    Synonyme
    CTLA8 antikoerper, IL-17 antikoerper, IL-17A antikoerper, IL17 antikoerper, Ctla-8 antikoerper, Ctla8 antikoerper, Il17 antikoerper, ChIL-17 antikoerper, IL-17F antikoerper, IL17A antikoerper, CTLA-8 antikoerper, interleukin 17A antikoerper, IL17A antikoerper, Il17a antikoerper
    Hintergrund
    IL17-A (also known as Interleukin-17) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC. Anti-IL-17A antibody is ideal for investigators involved in Immunology research.
    Synonyms: Interleukin-17, IL-17, IL-17A, Interleukin-17A, Cytotoxic T-Lymphocyte-associated Antigen 8, CTLA8.
    Gen-ID
    3605, 42542803
    UniProt
    Q16552
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