CA 19-9 Antikörper

Produktnummer ABIN1042585

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CA 19-9 in ELISA, FACS, IHC (p), WB und IHC (fro). Er zeigt eine Reaktivität gegenüber Human und wurde in 6+ Publikationen erwähnt.

Kurzübersicht für CA 19-9 Antikörper (ABIN1042585)

Target: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CA 19-9 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 121SLE

Produktdetails anti-CA 19-9 Antikörper

Aufreinigung: IgM specific affinity chromatography

Immunogen: Ten precipitin lines obtained after immunodiffusion using monoclonal antibody NS 19-9 and mucins isolated from an ovarian cyst of a OLe (a+b-) patient

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Optimal antibody dilution should be determined by titration, however as a guideline try at 2 μg/mL on FFPE tissue

Kommentare:

Myeloma, fusion partners: Spleen cells from immunised BALB/c mice were fused with cells of the Sp2/0 myeloma line

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Purified antibody in phosphate buffered saline containing 10 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Referenzen für anti-CA 19-9 Antikörper (ABIN1042585)

Partyka, Maupin, Brand, Haab: "Diverse monoclonal antibodies against the CA 19-9 antigen show variation in binding specificity with consequences for clinical interpretation." in: Proteomics, Vol. 12, Issue 13, pp. 2212-20, (2012) (PubMed).

Schnegelsberg, Schumacher, Valentiner: "Lectin histochemistry of metastasizing and non-metastasizing breast and colon cancer cells." in: Anticancer research, Vol. 31, Issue 5, pp. 1589-97, (2011) (PubMed).

Shi, Gao, Wang, Wang, Tian, Zhu, Shen, Qin: "CD133(+) gallbladder carcinoma cells exhibit self-renewal ability and tumorigenicity." in: World journal of gastroenterology : WJG, Vol. 17, Issue 24, pp. 2965-71, (2011) (PubMed).

Köhler, Ullrich, Richter, Schumacher: "E-/P-selectins and colon carcinoma metastasis: first in vivo evidence for their crucial role in a clinically relevant model of spontaneous metastasis formation in the lung." in: British journal of cancer, Vol. 102, Issue 3, pp. 602-9, (2010) (PubMed).

Rye, Bovin, Vlasova, Molodyk, Baryshnikov, Kreutz, Garinther, Schultes, Noujaim, Madiyalakan, Magnani, Nilsson, Nilsson, Nustad, Norum, Bell, Cao, Suresh, Very, Freeman, Yeung, Hilgers: "Summary report on the ISOBM TD-6 workshop: analysis of 20 monoclonal antibodies against Sialyl Lewisa and related antigens. Montreux, Switzerland, September 19-24, 1997." in: Tumour biology, Vol. 19, Issue 5, pp. 390-420, (1998) (PubMed).

Bara, Mollicone, Herrero-Zabaleta, Gautier, Daher, Oriol: "Ectopic expression of the Y (Ley) antigen defined by monoclonal antibody 12-4LE in distal colonic adenocarcinomas." in: International journal of cancer. Journal international du cancer, Vol. 41, Issue 5, pp. 683-9, (1988) (PubMed).

Details zu CA 19-9

Target: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Andere Bezeichnung: CA19-9   

Hintergrund: Synonyms:
Sialyl Lewis (a) antibody,Sialyl Lewis(a) antibody,Sialyl Lewisa antibody