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ANTXR1 Produkte

(anthrax Toxin Receptor 1 (ANTXR1))
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008].

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Ausgewählte ANTXR1 Kategorien

ANTXR1 Antikörper

High quality antibodies with extensive validation data.

ANTXR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

ANTXR1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ANTXR1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, WB
Validierungen
  • (2)
Kat. Nr. ABIN185280
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, WB
Validierungen
  • (2)
Kat. Nr. ABIN205769
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation EIA, IHC (p), WB
Validierungen
  • (2)
Kat. Nr. ABIN499363
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene ANTXR1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6964899
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1122056
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1122057
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ANTXR1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3128696
Menge 0.25 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3088755
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3088756
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ANTXR1 Produkten

Jayawardena, Burga, Easingwood, Takizawa, Wolf, Bostina: "Structural basis for anthrax toxin receptor 1 recognition by Seneca Valley Virus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 46, pp. E10934-E10940, (2019) (PubMed).

Matsuda, Ohga, Hida, Muraki, Tsuchiya, Kurosu, Akino, Shih, Totsuka, Klagsbrun, Shindoh, Hida: "Isolated tumor endothelial cells maintain specific character during long-term culture." in: Biochemical and biophysical research communications, Vol. 394, Issue 4, pp. 947-54, (2010) (PubMed).

Wei, Lu, Chaudry, Leppla, Cohen: "The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin." in: Cell, Vol. 124, Issue 6, pp. 1141-54, (2006) (PubMed).

Werner, Kowalczyk, Faundez: "Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton." in: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23227-36, (2006) (PubMed).

Rainey, Wigelsworth, Ryan, Scobie, Collier, Young: "Receptor-specific requirements for anthrax toxin delivery into cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13278-83, (2005) (PubMed).

Hotchkiss, Basile, Spring, Bonuccelli, Lisanti, Terman: "TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen." in: Experimental cell research, Vol. 305, Issue 1, pp. 133-44, (2005) (PubMed).

Sanz, Calasanz, Andreu, Richard, Prosper, Fernandez-Luna: "NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells." in: The Biochemical journal, Vol. 384, Issue Pt 2, pp. 281-6, (2004) (PubMed).

Nanda, Carson-Walter, Seaman, Barber, Stampfl, Singh, Vogelstein, Kinzler, St Croix: "TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI)." in: Cancer research, Vol. 64, Issue 3, pp. 817-20, (2004) (PubMed).

Widlak, Li, Wang, Garrard: "Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I." in: The Journal of biological chemistry, Vol. 276, Issue 51, pp. 48404-9, (2001) (PubMed).

Parrish, Li, Klotz, Ledwich, Wang, Xue: "Mitochondrial endonuclease G is important for apoptosis in C. elegans." in: Nature, Vol. 412, Issue 6842, pp. 90-4, (2001) (PubMed).

Synonyme und alternative Namen zu ANTXR1

anthrax toxin receptor 1 (ANTXR1), anthrax toxin receptor 1 (Antxr1), 2310008J16Rik, 2810405N18Rik, Antrx1, ANTXR1, ATR, TEM8, Tem8

Bezeichner auf Proteinebene für ANTXR1

  • anthrax toxin receptor 1
  • tumor endothelial marker 8
  • anthrax toxin receptor 1-like
  • 2310008J16Rik
  • 2810405N18Rik
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