Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity. [provided by RefSeq, Jul 2008].
ANXA1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Aktuelle Publikationen für unsere Annexin a1 Proteine
Legiawati, Bramono, Indriatmi, Yunir, Setiati, Jusman, Purwaningsih, Wibowo, Danarti: "Oral and Topical Centella asiatica in Type 2 Diabetes Mellitus Patients with Dry Skin: A Three-Arm Prospective Randomized Double-Blind Controlled Trial." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2020, pp. 7253560, (2020) (PubMed).
Hamelin-Peyron, Vlaeminck-Guillem, Haïdous, Schwall, Poznanovi?, Gorius-Gallet, Michel, Larue, Guillotte, Ruffion, Choquet-Kastylevsky, Ataman-Önal: "Prostate cancer biomarker annexin A3 detected in urines obtained following digital rectal examination presents antigenic variability." in: Clinical biochemistry, Vol. 47, Issue 10-11, pp. 901-8, (2014) (PubMed).
Bhattacharjee, Ahamed, Pawlinski, Liu, Mackman, Ruf, Edgington: "Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1." in: Circulation research, Vol. 102, Issue 4, pp. 457-64, (2008) (PubMed).