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ANK2 Produkte

(Ankyrin 2, Neuronal (ANK2))

Kategorien

This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011].

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Ausgewählte ANK2 Kategorien

ANK2 Antikörper

High quality antibodies with extensive validation data.

ANK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene ANK2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, ICC, IF
Validierungen
  • (4)
Kat. Nr. ABIN1027715
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ICC, IF
Validierungen
  • (3)
Kat. Nr. ABIN2485079
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ICC, IF
Validierungen
  • (3)
Kat. Nr. ABIN2485091
Menge 100 μg
Datenblatt Datenblatt

Empfohlene ANK2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Sheep
Analytical Method Quantitative
Validierungen
Kat. Nr. ABIN1050393
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Monkey
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1050392
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Chicken
Analytical Method Quantitative
Validierungen
Kat. Nr. ABIN1050391
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ANK2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2714726
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ANK2 Produkten

Chang, Zollinger, Susuki, Sherman, Makara, Brophy, Cooper, Bennett, Mohler, Rasband: "Glial ankyrins facilitate paranodal axoglial junction assembly." in: Nature neuroscience, Vol. 17, Issue 12, pp. 1673-81, (2014) (PubMed).

Le Bras, Fréal, Czarnecki, Legendre, Bullier, Komada, Brophy, Davenne, Couraud: "In vivo assembly of the axon initial segment in motor neurons." in: Brain structure & function, Vol. 219, Issue 4, pp. 1433-50, (2014) (PubMed).

Trinh-Trang-Tan, Bigot, Picot, Lecomte, Kordeli: "AlphaII-spectrin participates in the surface expression of cell adhesion molecule L1 and neurite outgrowth." in: Experimental cell research, Vol. 322, Issue 2, pp. 365-80, (2014) (PubMed).

Carney, Milanese, van Nierop, Li, Oliet, Smit, Bonanno, Verheijen: "Proteomic analysis of gliosomes from mouse brain: identification and investigation of glial membrane proteins." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5918-27, (2014) (PubMed).

Ho, Zollinger, Chang, Xu, Cooper, Stankewich, Bennett, Rasband: "A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier." in: Nature neuroscience, Vol. 17, Issue 12, pp. 1664-72, (2014) (PubMed).

Zhang, Susuki, Zollinger, Dupree, Rasband: "Membrane domain organization of myelinated axons requires ?II spectrin." in: The Journal of cell biology, Vol. 203, Issue 3, pp. 437-43, (2013) (PubMed).

Galiano, Jha, Ho, Zhang, Ogawa, Chang, Stankewich, Mohler, Rasband: "A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly." in: Cell, Vol. 149, Issue 5, pp. 1125-39, (2012) (PubMed).

Huff, Shi, Sun, Wu, Shi, Cheng: "Real-time CARS imaging reveals a calpain-dependent pathway for paranodal myelin retraction during high-frequency stimulation." in: PLoS ONE, Vol. 6, Issue 3, pp. e17176, (2011) (PubMed).

Susuki, Raphael, Ogawa, Stankewich, Peles, Talbot, Rasband: "Schwann cell spectrins modulate peripheral nerve myelination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 19, pp. 8009-14, (2011) (PubMed).

Lysakowski, Gaboyard-Niay, Calin-Jageman, Chatlani, Price, Eatock: "Molecular microdomains in a sensory terminal, the vestibular calyx ending." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 27, pp. 10101-14, (2011) (PubMed).

Synonyme und alternative Namen zu ANK2

ankyrin 2 (ANK2), ankyrin 2, brain (Ank2), ankyrin 2 (Ank2), ankyrin-2 (LOC539238), ankyrin 2b, neuronal (ank2b), ankyrin-2 (LOC100465763), AI835472, ANK-2, Ank-2, ANK2, ank2, Ank3, ANKB, AW491075, brank-2, CHANK2, LQT4, zgc:101738

Bezeichner auf Proteinebene für ANK2

  • ankyrin B
  • ankyrin, brain
  • ankyrin-2
  • ankyrin-2, nonerythrocytic
  • non-erythroid ankyrin
  • ankyrin-B
  • brain ankyrin
  • ankyrin 2, brain
  • ankyrin 3, epithelial
  • ankyrin 2, neuronal
  • ankyrin-2-like
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