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anti-Human PRKAB1 Antikörper:
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Dog (Canine) Monoclonal PRKAB1 Primary Antibody für IF, WB - ABIN968185
Michell, Stapleton, Mitchelhill, House, Katsis, Witters, Kemp: Isoform-specific purification and substrate specificity of the 5'-AMP-activated protein kinase. in The Journal of biological chemistry 1996
Show all 4 Pubmed References
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
5'-AMP-activated protein kinase subunit beta-1
, AMPK-activated protein kinase beta-1 subunit
, 5'AMP-activated protein kinase beta-1 non-catalytic subunit
, protein kinase, AMP-activated, beta 1 non-catalytic subunit
, AMP-activated protein kinase beta 1 non-catalytic subunit
, AMPK subunit beta-1
, 5'-AMP-activated protein kinase beta-1 subunit
, AMP-activated protein kinase beta subunit
, AMPK beta -1 chain
, AMPK beta 1
, protein kinase, AMP-activated, noncatalytic, beta-1
, 5'-AMP-activated protein kinase 40 kDa subunit
, 5'-AMP-activated protein kinase, beta subunit
, 5-AMP-activated protein kinase beta subunit
, AMPK beta-1 chain