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HMGCR Proteine

8 Treffer:

3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 1-887) protein (rho-1D4 tag) Protein

Crystallography grade HMGCR Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Produktnummer ABIN3134765
$8,446.36
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
0.25 mg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 60 bis 65 Werktagen

3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 1-888) protein (rho-1D4 tag) Protein

Crystallography grade HMGCR Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Produktnummer ABIN3092943
$12,040.50
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
0.5 mg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 60 bis 65 Werktagen

3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 1-835) protein (GST tag) Protein

HMGCR Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Produktnummer ABIN1306814
$390.67
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
2 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen

3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 638-887) protein (T7 tag,His tag) Protein

HMGCR Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant ≥ 99 % ELISA, IP, SDS, WB
Produktnummer ABIN6237002
$400.00
Zzgl. Versandkosten $45.00
50 μg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 12 bis 15 Werktagen

3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 588-887), (partial) protein (His tag) Protein

HMGCR Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5709669
$501.60
Zzgl. Versandkosten $45.00
100 μg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 Werktagen

3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 426-888) (Active) protein (GST tag) Protein

HMGCR Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant ≥90 % by SDS-PAGE SDS Active
Produktnummer ABIN2506881
$85.00
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
100 μg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 2 bis 3 Werktagen

3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 426-888) protein (His tag) Protein

HMGCR Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE.
Produktnummer ABIN7035852
$897.00
Zzgl. Versandkosten $45.00
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 9 bis 10 Werktagen

3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) (AA 426-888) protein (His tag) Protein

HMGCR Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE.
Produktnummer ABIN7035853
$897.00
Zzgl. Versandkosten $45.00
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 9 bis 10 Werktagen
  • Typ Protein
    • Protein
  • Target 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
    • 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
    • Hemagglutinin (HA)
    • Hemoglobin beta (HBB)
    • Ribosome Binding Factor A (RBFA)
    • Triosephosphate Isomerase 1 (TPI1)
    • S-Adenosyl-Methionine Synthase (METK)
    • Hemoglobin, alpha 1 (HBA1)
    • SARS-CoV-2 Spike
    • Myoglobin (MB)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • Thymidylate Kinase (Tmk)
    • Lipoyl synthase (lipA)
    • Growth Hormone 1 (GH1)
    • Interferon gamma (IFNG)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Aspartate Carbamoyltransferase (PYRB)
    • Uracil-DNA Glycosylase (UNG)
    • Malate Dehydrogenase (MDH)
    • Phosphoglucosamine Mutase (GLMM)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • phosphatidylserine Decarboxylase (PISD)
    • Cysteinyl-tRNA Synthetase 2, Mitochondrial (Putative) (CARS2)
    • tRNA Methyltransferase 5 (TRMT5)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Interleukin 6 (IL6)
    • Interleukin 2 (IL2)
    • Cytochrome C, Somatic (CYCS)
    • Interleukin 4 (IL4)
    • Epidermal Growth Factor Receptor (EGFR)
    • CD40 Ligand (CD40LG)
    • Gp120
    • Porphobilinogen Deaminase (HEMC)
    • Plasminogen Activator Inhibitor 1 (SERPINE1)
    • Superoxide Dismutase 1, Soluble (SOD1)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • 1-(5-Phosphoribosyl)-5-[(5-Phosphoribosylamino)methylideneamino] Imidazole-4-Carboxamide Isomerase (APG10)
    • Interleukin 10 (IL10)
    • Interleukin 8 (IL8)
    • Interleukin 1, beta (IL1B)
    • Prolactin (PRL)
    • Adenosylhomocysteinase (AHCY)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Ferrochelatase, HEMH (HEMH)
    • Thymidylate Synthase (THYA)
    • Programmed Cell Death 1 (PDCD1)
    • SARS-CoV-2 Spike S1
    • Thymidine Kinase 1, Soluble (TK1)
    • Uracil Phosphoribosyltransferase (UPP)
    • beta-2-Microglobulin (B2M)
    • Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
    • Insulin-Like Growth Factor 1 (IGF1)
  • Anwendung
    • SDS-PAGE (SDS)
    • ELISA
    • Western Blotting (WB)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunoprecipitation (IP)
  • Reaktivität
    • Human
    • Maus
    • Ratte
  • Abbildungen verfügbar
  • Wirt
    • Escherichia coli (E. coli)
    • Insektenzellen
    • Baculovirus infected Insect Cells
    • Wheat germ
  • Bindungsspezifität
    • AA 426-888
    • AA 1-835
    • AA 1-887
    • AA 1-888
    • AA 588-887
    • AA 638-887
    • partial
  • Konjugat
    • Unkonjugiert
    • His tag
    • GST tag
    • rho-1D4 tag
    • T7 tag,His tag
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Biologische Aktivität
    • Active
  • Grade
    • Crystallography grade

HMGCR Protein Überblick

Protein Überblick

HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with HMGCR

  • 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) Antikörper
  • 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog (hmgcr.L) Antikörper
  • 3-hydroxy-3-methylglutaryl-Coenzyme A reductase (Hmgcr) Antikörper
  • 3-hydroxy-3-methylglutaryl-CoA reductase (Hmgcr) Antikörper
  • HMG Coenzyme A reductase (Hmgcr) Antikörper
  • 3-hydroxy-3-methylglutaryl-CoA reductase b (hmgcrb) Antikörper
  • 3H3M Antikörper
  • BcDNA:LD15354 Antikörper
  • bro1 Antikörper
  • bs32f05.y1 Antikörper
  • CG10367 Antikörper
  • clb Antikörper
  • Dmel\\CG10367 Antikörper
  • DmHMG-CoAr Antikörper
  • Hmg Antikörper
  • hmg-coa-r Antikörper
  • HmG-CoAR Antikörper
  • hmgc Antikörper
  • HMGCoAr Antikörper
  • HMGCoARr Antikörper
  • hmgcr Antikörper
  • hmgcr2 Antikörper
  • HMGCR_Dm Antikörper
  • HMGR Antikörper
  • hmgrc Antikörper
  • im:6912716 Antikörper
  • l(3)01152 Antikörper
  • l(3)04684 Antikörper
  • LDLCQ3 Antikörper
  • Red Antikörper
  • zgc:110746 Antikörper

Bezeichner auf Proteinebene für HMGCR

3-hydroxy-3-methylglutaryl-Coenzyme A reductase , 3-hydroxy-3-methylglutaryl coenzyme A reductase/HMG-CoA reductase , 3-hydroxy-3-methylglutaryl-coenzyme A reductase , 3-hydroxy-3-methylglutaryl CoA reductase (NADPH) , HMG-CoA reductase , hydroxymethylglutaryl-CoA reductase , 3-hydroxy-3-methylglutaryl CoA reductase , 3-hydroxy-3-methylglutaryl-CoA reductase , 3-Hydroxy-3-Methylglutaryl CoA reductase , 3-hydroxy-3-methylglutaryl coenzyme A reductase , CG10367-PA , HMG coenzyme A reductase , HMGCo-A reductase , HMGCoA reductase , Hmg-CoA-reductase , Hmgcr-PA , columbus , lethal (3) 04684 , 3-alpha-hydroxy-3-methylglutaryl-CoA reductase , 3-hydroxy-3-methylglutaryl-CoA reductase b , 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b , hmgcr1b , hmgrb

GENE ID SPEZIES
479182 Canis lupus familiaris
100144446 Sus scrofa
395145 Gallus gallus
3156 Homo sapiens
397750 Xenopus laevis
407159 Bos taurus
100173499 Pongo abelii
15357 Mus musculus
25675 Rattus norvegicus
100357791 Oryctolagus cuniculus
42803 Drosophila melanogaster
100756363 Cricetulus griseus
100726509 Cavia porcellus
100065577 Equus caballus
541479 Danio rerio

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