Afadin Produkte
(Afadin (MLLT4))
Kategorien
This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6\;11)(q27\;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011].
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Ausgewählte Afadin Kategorien
Afadin Antikörper
High quality antibodies with extensive validation data.
Empfohlene Afadin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7143570
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7242503
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF, IP
Validierungen
- (5)
- (2)
Kat. Nr.
ABIN968143
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene Afadin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN5777013
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Afadin Produkten
: "Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation." in: Nature structural & molecular biology, Vol. 23, Issue 2, pp. 155-63, (2016) (PubMed).: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).
: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).
: "Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosin." in: The Journal of cell biology, Vol. 147, Issue 7, pp. 1569-82, (2000) (PubMed).
: "Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1." in: The Journal of biological chemistry, Vol. 275, Issue 36, pp. 27979-88, (2000) (PubMed).
: "The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain." in: The Journal of cell biology, Vol. 144, Issue 2, pp. 361-71, (1999) (PubMed).
: "Identification of AF-6 and canoe as putative targets for Ras." in: The Journal of biological chemistry, Vol. 271, Issue 2, pp. 607-10, (1996) (PubMed).
: "Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation." in: Cancer research, Vol. 53, Issue 23, pp. 5624-8, (1994) (PubMed).
Synonyme und alternative Namen zu Afadin
afadin, adherens junction formation factor (AFDN), afadin, adherens junction formation factor L homeolog (afdn.L), afadin, adherens junction formation factor a (afdna), afadin (LOC589923), afadin (LOC100177180), afadin, adherens junction formation factor (afdn), afadin, adherens junction formation factor (Afdn), 5033403D15Rik, af-6, Af-6, af6, AF6, Af6, Afadin, Gm314, I-afadin, MLLT4, RP3-431P23.3, S-afadin, si:ch211-278j12.1Bezeichner auf Proteinebene für Afadin
- myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
- afadin-like
- ALL1-fused gene from chromosome 6 protein
- afadin
- protein AF-6
- myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog
- protein Af-6
- myeloid/lymphoid or mixed-lineage leukemia 4
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