This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme\; binds mitotic arrest deficient 2 protein\; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008].
ADAM17
Spezies: Human
Wirt: Mammalian Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ADAM17
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ADAM17
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Wang, Huang, Nayak, Matthews, Warburton, Shi, Sanchez-Esteban: "Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin ?6?1-ADAM17/tumor necrosis factor-?-converting enzyme (TACE) signaling pathway." in: The Journal of biological chemistry, Vol. 288, Issue 35, pp. 25646-57, (2013) (PubMed).
Aliase für ADAM17 Proteine
ADAM metallopeptidase domain 17 (ADAM17) Proteine a disintegrin and metallopeptidase domain 17 (Adam17) Proteine ADAM metallopeptidase domain 17b (adam17b) Proteine ADAM metallopeptidase domain 17 L homeolog (adam17.L) Proteine ADAM metallopeptidase domain 17 (Adam17) Proteine ADAM metallopeptidase domain 17a (adam17a) Proteine adam17 Proteine ADAM18 Proteine adam18 Proteine CD156B Proteine CD156b Proteine cd156b Proteine CSVP Proteine csvp Proteine fc20b01 Proteine NISBD Proteine si:dkey-81b15.2 Proteine TACE Proteine Tace Proteine tace Proteine wu:fc20b01 Proteine zgc:63886 Proteine