anti-MMP2 (MMP2) Antikörper

Horse (Equine) Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

1. study demonstrated that matrix metalloproteinase 1 (zeige MMP1 Antikörper) and 2 might be fundamental for events related to equine tissue remodeling, which occurs during follicular development

Fruit Fly (Drosophila melanogaster) Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

1. inhibition of ECM (zeige MMRN1 Antikörper) degradation by inhibition of matrix metalloproteinase 2 (Mmp2) to preserve the extracellular environment characteristics of young adults led to increased dendrite regeneration

2. Data indicate that matrix metalloproteinases mmp1 (zeige MMP1 Antikörper) and mmp2 mutants have distinct heart phenotypes.

3. We also show that follicular OA-Oamb signaling induces Mmp2 enzymatic activation but not Mmp2 protein expression, likely via intracellular Ca2 (zeige CA2 Antikörper)+ as the second messenger.

4. Finally, matrix metalloproteinase 2 (Mmp2), a type of protease thought to facilitate mammalian ovulation, is expressed in mature follicle and corpus luteum cells.

5. As a Wnt (zeige WNT4 Antikörper) signaling antagonist, MMP2 cleaves the glypican (zeige GPC1 Antikörper), reducing the ability of Dlp (zeige DMD Antikörper) to interact with the Wnt (zeige WNT4 Antikörper) ligand and promote its distribution.

6. Matrix metalloproteinase 2 is required for fat-body remodeling in Drosophila

7. Drosophila MMP2 regulates the matrix molecule faulty attraction (Frac) to promote motor axon targeting in Drosophila.

8. Dendrite reshaping of adult Drosophila sensory neurons requires matrix metalloproteinase MMP2-mediated modification of the basement membranes

9. Mmp2 expression in the developing air sac (zeige ADCY10 Antikörper) is controlled by the Drosophila FGF homolog Branchless and then participates in a negative feedback and lateral inhibition mechanism that defines the precise pattern of FGF signaling.

10. findings demonstrate a critical role for Mmp2 in tubulogenesis post-induction, and implicate Mmp2 in regulating dynamic and essential changes to the extracellular matrix

Zebrafish Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

1. Mmp2 facilitates endothelial-to-hematopoietic transition via ECM (zeige MMRN1 Antikörper) remodeling.

2. Dexamethasone and hydrocortisone alter expression and activity of MMP-2 and MMP-9 (zeige MMP9 Antikörper) in the embryonic zebrafish.

Mouse (Murine) Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

1. Diet and exercise affect atheromatous MMP2/9 activity by modulating the systemic inflammatory milieu, with sVCAM-1, resistin, and adiponectin closely interacting with each other and with visceral fat.

2. calpains inhibition plays crucial roles in vascular restenosis by preventing neointimal hyperplasia at the early stage via suppression of the MMP2/TGF-beta1 (zeige TGFB1 Antikörper) pathway.

3. Aneurysmal-prone factors induced HIF-1alpha (zeige HIF1A Antikörper) can cause overexpression of MMP-2 and MMP-9 (zeige MMP9 Antikörper) and promote aneurysmal progression.

4. These studies illustrated an important role of MMP2 in cognitive and motor behaviors and confirm its importance in NPC (zeige NPC1 Antikörper) activities crucial to brain development, growth and response to and recovery from injury.

5. Secretagogin (zeige SCGN Antikörper)-dependent MMP2 release from neurons regulates neuroblast migration.

6. matrix metalloproteinase 2 (Mmp2) transcript is a target of miR (zeige MLXIP Antikörper)-195a-3p, and that silencing Mmp2 phenocopied the reduced proliferation and migration of MSCs. The therapeutic potential of miR (zeige MLXIP Antikörper)-195a-3p as an angiogenesis inhibitor was also demonstrated in a laser-induced choroidal neovascularization mouse model.

7. developed a novel selective radiolabeled MMP2/9 inhibitor, suitable for single photon emission computed tomography (SPECT) imaging that effectively targets atherosclerotic lesions in mice

8. MMP-2 and MMP-9 (zeige MMP9 Antikörper) have roles in early stages of experimental autoimmune encephalomyelitis induction; MMP-9 (zeige MMP9 Antikörper) from an immune cell source is required in EAE for initial infiltration of leukocytes into the central nervous system

9. This study illustrated that tumour-derived MMP2 has at least two roles in tumour malignancy; to enhance tumour invasiveness by degrading the extracellular matrix and to enhance tumour growth by promoting vessel maturation and function.

10. MMP-2 and -9 expression were suppressed significantly by treatment with SB-3CT. The data demonstrated, for the first time, that SB-3CT strongly reduced corneal lymphangiogenesis and macrophage infiltration during inflammation.

Human Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

1. MMP-2 serum level and circulating tumor cells show the potential to predict CNS metastases and overall survival in breast cancer patients; CTCs and MMP-9 (zeige MMP9 Antikörper) serum level could be a promising therapy response marker in castration resistant prostate cancer patients

2. RhoGDIbeta overexpression led to downregulation of miR (zeige MLXIP Antikörper)-200c, whereas miR (zeige MLXIP Antikörper)-200c was able directly to target 3'-UTR (zeige UTS2R Antikörper) of jnk2mRNA and attenuated JNK2 (zeige MAPK9 Antikörper) protein translation, which resulted in attenuation of Sp1mRNA and protein expression in turn, inhibiting Sp1 (zeige PSG1 Antikörper)-dependent MMP-2 transcription.

3. both HBEGF (zeige HBEGF Antikörper) upregulation and apoptosis were rescued by exogenous MMP2

4. MMP-2 (and MMP-1 (zeige MMP1 Antikörper) and MMP-3 (zeige MMP3 Antikörper)) are independently associated with markers of arterial stiffening in patients with type 1 diabetes.

5. The results suggest that SH3GL2 (zeige SH3G2 Antikörper) suppresses migration and invasion behaviors of glioma cells through negatively regulating STAT3 (zeige STAT3 Antikörper)/MMP2 signaling.

6. MMP-2 (-1306 C/T) polymorphism is associated with exudative age-related macular degeneration development in younger males.

7. these results suggest that Ascochlorin inhibits cell migration and invasion by blocking FAK (zeige PTK2 Antikörper) and JAK (zeige JAK3 Antikörper)/STAT (zeige STAT1 Antikörper) signaling, resulting in reduced MMP-2 activity.

8. We found that overexpression of AEG-1 (zeige MTDH Antikörper) in PTC (zeige F9 Antikörper) was positively correlated with lymph node metastasis and MMP2/9 expression. Knockdown of AEG-1 (zeige MTDH Antikörper) reduced the capacity of migration and invasion through downregulation of MMP2/9 in thyroid cancer cells. Furthermore, we firstly found that AEG-1 (zeige MTDH Antikörper) interacted with MMP9 (zeige MMP9 Antikörper) in thyroid cancer cells.

9. MMP2/TIMP4 (zeige TIMP4 Antikörper) ratio is a marker of disease severity and right ventricular function as well as a predictor for survival and time to clinical worsening in idiopathic pulmonary arterial hypertension.

10. The aim was to examine if the serum concentrations of elastin (zeige ELN Antikörper)-related proteins correlate to signs of cardiovascular diseases in patients with Diabetes mellitus type 2.

Cow (Bovine) Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

1. this study shows that differential FFAR1 (zeige FFAR1 Antikörper) signaling is associated with gene expression or gelatinase granule release in bovine neutrophils

2. NADPH oxidase (zeige NOX1 Antikörper) plays an important role in proMMP-2 expression and activation and MMP-2 mediated SMC (zeige DYM Antikörper) proliferation occurs through the involvement of Spm (zeige NPC1 Antikörper)-Cer (zeige CBLN1 Antikörper)-S1P (zeige MBTPS1 Antikörper) signaling axis under ANG II (zeige AGT Antikörper) stimulation of PASMCs

3. The expression patterns of MMP1 (zeige MMP1 Antikörper), MMP2, and MMP8 (zeige MMP8 Antikörper) were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1 (zeige MMP1 Antikörper), MMP2, and MMP8 (zeige MMP8 Antikörper) expression levels with meat quality traits were analyzed in cattle. The expression of MMP1 (zeige MMP1 Antikörper), MMP2, and MMP8 (zeige MMP8 Antikörper) were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.

4. The results showed that a decrease in MMP-1 (zeige MMP1 Antikörper) and MMP-2 gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.

5. Activation of cytosolic MMP-9 (zeige MMP9 Antikörper) and MMP-2 was investigated in the retinal endothelial cells incubated in high glucose for 6-96 h, and correlated with their mitochondrial accumulation and mitochondrial damage.

6. Data indicate the involvement of PKC-alpha (zeige PKCa Antikörper) in proMMP-2 activation and inhibition of TIMP-2 (zeige TIMP2 Antikörper) expression by NF-kappaB (zeige NFKB1 Antikörper)-MT1-MMP (zeige MMP14 Antikörper)-dependent and -independent pathway.

7. Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2; MMP-14 (zeige MMP14 Antikörper)) in endometrial stromal cells; expression of stromal MMPs is significantly higher in coculture with epithelial cells.

8. Adding pure bovine MMP-2 to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase (zeige CA-P60A Antikörper) activity, but the pretreatment with TIMP-2 (zeige TIMP2 Antikörper) inhibits the increase in the enzyme activity

9. A differential pattern of matrix metalloproteinase-2 and Tissue inhibitor metalloproteinase-2 was observed in cow uteri with adenomyosis.

10. MMP-14 (zeige MMP14 Antikörper), MMP-2 and TIMP-2 (zeige TIMP2 Antikörper) are co-localized in the fetal compartment and therefore could influence the timely release of fetal membranes in cattle.

Pig (Porcine) Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

1. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (zeige MMP9 Antikörper), TIMP1 (zeige TIMP1 Antikörper), and NGAL (zeige LCN2 Antikörper) (also MMP2 in 220 kDa complex) without proteolytic activity.

2. Data demonstrate for the first time that MMP2 and MMP9 (zeige MMP9 Antikörper) are expressed in swine ovarian follicle both in theca and granulosa layers.

3. FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (zeige MMP9 Antikörper) and MMP-2, caspase-3 (zeige CASP3 Antikörper) and BDNF (zeige BDNF Antikörper)

4. MMP-2 may play an important role in regulating MLC1 turnover in the heart under normal physiological conditions

5. Oxygen for newborn resuscitation increases MMP-2/-9 activity resulting in tissue damage and influencing remodeling processes.

6. PI3K-dependent regulation of MT1-MMP (zeige MMP14 Antikörper) protein synthesis and subsequent activation of latent MMP-2 as critical events in neointimal hyperplasia after vascular injury.

7. MMP-2 processes dental sialophosphoprotein into smaller subunits in the dentin matrix during odontogenesis

8. contribution of MMPs to the inflammatory breakdown of the blood-CSF (zeige CSF2 Antikörper) barrier in vitro

9. The levels of matrix metalloproteinase-2 and matrix metalloproteinase-9 (zeige MMP9 Antikörper) in the corpus luteum of swine during luteolysis are reported.

10. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (zeige VEGFA Antikörper), pro-MMP-9 (zeige MMP9 Antikörper), MMP-2, VEGFR-1 (zeige FLT1 Antikörper), VEGFR-2 (zeige KDR Antikörper), and TIMP-1 (zeige TIMP1 Antikörper), which may contribute to the development of venous stenosis.

Rabbit Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

1. Selenium suppressed high-fat diet-induced MMP2 over-expression in vivo by improving lipid metabolism.

2. Inflammatory factors such as TNF-alpha (zeige TNF Antikörper) can stimulate MMP-2/9 activity in corneal epithelium cells. This may be a potential manipulating mechanism of MMP expression in the pathogenesis of corneal diseases

3. Results provide evidence that MMP-2 bears the potentiality to cleave alpha-DG enriched from rabbit skeletal muscle indicating that this degradation indeed might also occur in vivo.

4. In conclusion, MMP-2 could be responsible for the proteolysis of dystrophin (zeige DMD Antikörper).

5. Castor (zeige CASZ1 Antikörper) oil polymer induces bone formation with high matrix metalloproteinase-2 expression.

6. MMP2 spinal cord expression is increased in cervical spondylotic myelopathy.

7. Ulinastatin (zeige AMBP Antikörper) effectively inhibited the increased expression of MMP-2, MMP-3 (zeige MMP3 Antikörper), and iNOS (zeige NOS2 Antikörper) in degenerated NP cells induced by IL-1beta (zeige IL1B Antikörper) in vitro.

8. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2, MMP-9 (zeige MMP9 Antikörper) and TIMP-1 (zeige TIMP1 Antikörper) in rabbits with acute paraquat poisoning.

9. The RNA interference targeting COX-2 (zeige COX2 Antikörper) can effectively inhibit the expression of COX-2 (zeige COX2 Antikörper) and MMP-2 in IL-1alpha stimulated rabbit corneal stromal cells in vitro.

10. Our results strongly suggest that ischaemic postconditioning may exert part of its cardioprotective effects through the inhibition of MMP-2 activity.