Protein Überblick

This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with Immunoglobulin kappa Variable 1-27 (IGKV1-27)

• TNF alpha induced protein 3 (TNFAIP3) Antikörper

• A20 Antikörper
• OTUD7C Antikörper
• TNFA1P2 Antikörper

Bezeichner auf Proteinebene für IGKV1-27

OTU domain-containing protein 7C , TNF alpha-induced protein 3 , putative DNA-binding protein A20 , tumor necrosis factor alpha-induced protein 3 , tumor necrosis factor inducible protein A20 , zinc finger protein A20