Th1,Th2,Th17 Cytokine Standard

Produktnummer ABIN1379842

Kurzübersicht für Th1,Th2,Th17 Cytokine Standard (ABIN1379842)

Target: IL-2, IL-4, IL-6, IL-10, IL-17A, IFN-gamma

Applikation: Immunoassay (IA), Flow Cytometry (FACS)

Produktdetails

Reaktivität: Maus

Marke: BD™ Cytometric Bead Array,BD™

Produktmerkmale: The Mouse Th1/Th2/Th17 Cytokine Standards contains a mixture of individually lyophilized recombinant proteins made up of recombinant Mouse Interleukin (IL)-2, IL-4, IL-6, IL-10, IL-17A, Interferon-gamma (IFN-gamma), and Tumor Necrosis Factor (TNF). The reconstituted Mouse Th1/Th2/Th17 Cytokine Standards are designed for use as standard controls with the BD™ Cytometric Bead Array (CBA) Mouse Th1/Th2/TH17 Cytokine Kit (Cat. No. 560485). Please refer to the manual included with the BD™ Cytometric Bead Array (CBA) Mouse Th1/Th2/TH17 Cytokine Kit for further information

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized in an aqueous buffered solution containing BSA and ProClin™ 150.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the lyophilized standard at 4°C prior to reconstitution. Lyospheres from 1 vial of the Mouse Th1/Th2/Th17 Cytokine Standard, when reconstituted in 2.0 mL Assay Diluent, approximates the CBA activity of Mouse IL-2, IL-4, IL-6, IL-10, IL-17A, Interferon-γ (IFN-γ), and Tumor Necrosis Factor (TNF) at a concentration of 5000 pg/mL. Following reconstitution, maintain the Mouse Th1/Th2/Th17 Cytokine Standard at 4°C and use within 12 hours. Any unused reconstituted standard must be discarded after this period (do not store or reuse).

Referenzen

Curran, Montalvo, Yagita, Allison: "PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 9, pp. 4275-80, (2010) (PubMed).

Mattarollo, Yong, Tan, Frazer, Leggatt: "Secretion of IFN-gamma but not IL-17 by CD1d-restricted NKT cells enhances rejection of skin grafts expressing epithelial cell-derived antigen." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 10, pp. 5663-9, (2010) (PubMed).

Antigendetails

Target: IL-2, IL-4, IL-6, IL-10, IL-17A, IFN-gamma

Sub Type: Cocktail