alpha-conotoxin GI (alpha conotoxin GI)

Produktnummer ABIN1540039

Kurzübersicht für alpha-conotoxin GI (alpha conotoxin GI) (ABIN1540039)

Target: alpha-conotoxin GI

Applikation: Blocking Reagent (BR)

Produktdetails

Verwendungszweck: alpha-conotoxin G blocks nAChR receptors

Sequenz: Glu-Cys2-Cys3-Asn-Pro-Ala-Cys7-Gly-Arg-His-Tyr-Ser-Cys13-NH2Disulfide bonds between Cys2-Cys7, Cys3-Cys13

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Antigendetails

Target: alpha-conotoxin GI

Hintergrund: Alpha-conotoxin GI has been isolated from the venom of the cone snail Conus geographus. This conotoxin acts on postsynaptic membranes, which bind to the nicotinic acetylcholine receptor (nAChR). It Inhibits nAChR currents. The highestaffinity site for Cis the alpha/delta site on mouse muscle-derived BC3H-1 receptor, and the other site (alpha/gamma site) on nicotinic receptors from Torpedo californica electric organ.

Molekulargewicht: 1437.61 Da

CAS-Nummer: 76862-65-2