Sulindac Sulfone

Produktnummer ABIN1027865

Kurzübersicht für Sulindac Sulfone (ABIN1027865)

Produktdetails

Verwendungszweck: Sulindac metabolite

Produktmerkmale: Modulates beta-catenin-mediated effects.

Reinheit: >98 %

Chemical Name: {(1Z)-5-Fluoro-2-methyl-1-[4-(methylsulfonyl)benzylidene]-1H-inden-3-yl}acetic acid

Formel: C20H17FO4S

Löslichkeit: Soluble to 25 mM in DMSO, 3 mM in ethanol

Anwendungsinformationen

Kommentare:

Source: Synthetic.
Appearance: Yellow solid

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Solid

Vorsichtsmaßnahmen: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Handhabung: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Lagerung: -20 °C

Antigendetails

Hintergrund: Sulindac is a nonsteroidal anti-inflammatory drug that is known to prevent recurrence and reduce colorectal polyps. It is a prodrug that is metabolized to a sulfide and sulfone derivative in vivo. The mechanism of action of both is the selective induction of apoptosis. The anti-inflammatory properties of sulindac are mediated by COX inhibition.

Molekulargewicht: 372.41

CAS-Nummer: 59864-04-9