Phenylbutyrate Na

Produktnummer ABIN1027851

Kurzübersicht für Phenylbutyrate Na (ABIN1027851)

Produktdetails

Verwendungszweck: HDAC inhibitor

Produktmerkmale: Histone deacetylase inhibitor.

Reinheit: >98 %

Chemical Name: Sodium 4-phenylbutanoate, 4-PB

Formel: C10H11NaO2

Löslichkeit: Soluble to 1100 mM in water and 100 mM in DMSO

Anwendungsinformationen

Kommentare:

Source: Synthetic.
Appearance: White solid

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Solid

Vorsichtsmaßnahmen: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Handhabung: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Lagerung: -20 °C

Antigendetails

Hintergrund: Sodium phenylbutyrate is metabolized in the human body by beta-oxidation to phenylacetate, which is then conjugated with glutamine to phenylacetylglutamine, which is eliminated with urine. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of fetal hemoglobin through transcriptional activation of gamma-globin gene.

Molekulargewicht: 186.18

CAS-Nummer: 1716-12-7