Fumonisin B1
Kurzübersicht für Fumonisin B1 (ABIN1027813)
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Verwendungszweck
- Ceramide synthase inhibitor
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Produktmerkmale
- Blocks sphingolipid biosynthesis.
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Reinheit
- >98 %
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Chemical Name
- 2,2'-{(19-Amino-11,16,18-trihydroxy-5,9-dimethyl-6,7-icosanediyl)bis[oxy(2-oxo-2,1-ethanediyl)]}disuccinic acid
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Formel
- C34H59NO15
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Löslichkeit
- Soluble to 10 mM in DMSO
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Kommentare
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Source: Synthetic.
Appearance: Beige Solid -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Solid
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Vorsichtsmaßnahmen
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed R60- May impair fertility R61- May cause harm to the unborn child Hazard Phrases: H351 Precautionary Phrases: P281
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Handhabung
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed R60- May impair fertility R61- May cause harm to the unborn child Hazard Phrases: H351 Precautionary Phrases: P281
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Lagerung
- -20 °C
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Hintergrund
- Fumonisin B1 is the most prevalent member of a family of toxins. It is hepatotoxic and nephrotoxic in all animal species. It occupies the space and electrostatic interactions of both sphinganine and fatty acyl-CoA. Due to this mechanism of action, it has toxic effects in humans such as neural tube defects, esophageal cancer, acute mycotoxicosis, and various other carcinogenic effects. Another effect of exposure to FB1 is apoptosis.
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Molekulargewicht
- 721.83
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CAS-Nummer
- 116355-83-0
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