Nigericin

Produktnummer ABIN1027803

Kurzübersicht für Nigericin (ABIN1027803)

Produktdetails

Verwendungszweck: NALP3 activator

Produktmerkmale: Induces rapid intracellular acidification.

Reinheit: >98 %

Chemical Name: (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-{(2S,2'R,3'S,5R,5'R)-5'-[(2S,3S,5R,6R)-6-Hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-2,3'-dimethyloctahydro-2,2'-bifuran-5-yl}-9-metho xy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl]methyl}-3-methyltetrahydro-2H-pyran-2-yl]propanoic acid

Formel: C40H67NaO11

Löslichkeit: Soluble to 50 mM in DMSO and 20 mM in ethanol

Anwendungsinformationen

Kommentare:

Source: Synthetic.
Appearance: White to off-white Solid

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Solid

Vorsichtsmaßnahmen: Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302

Handhabung: Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302

Lagerung: -20 °C

Antigendetails

Hintergrund: Nigericin acts as a K and Na ionophore. It stimulates Ca release from mitochondrial stores by disruption of membrane potential.

Molekulargewicht: 746.94

CAS-Nummer: 28643-80-3