ACLY Produkte
(ATP Citrate Lyase (ACLY))
Kategorien
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte ACLY Kategorien
ACLY Antikörper
High quality antibodies with extensive validation data.
ACLY ELISA Kits
Reliable ELISA kits for a wide range of species.
ACLY Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ACLY Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Monkey, Mouse, Rat
Applikation
WB, ELISA, IHC, FACS, ICC
Validierungen
- (2)
- (7)
Kat. Nr.
ABIN1098143
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN7265716
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP
Validierungen
- (5)
Kat. Nr.
ABIN6136002
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ACLY ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965053
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965052
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965051
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ACLY Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7564780
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7551855
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121924
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ACLY Produkten
: "mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer." in: Oncotarget, Vol. 7, Issue 18, pp. 25224-40, (2018) (PubMed).: "The contribution of the citrate pathway to oxidative stress in Down syndrome." in: Immunology, Vol. 149, Issue 4, pp. 423-431, (2016) (PubMed).
: "Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells." in: International journal of cancer, Vol. 135, Issue 1, pp. 37-47, (2014) (PubMed).
: "Inactivation of ATP citrate lyase by Cucurbitacin B: A bioactive compound from cucumber, inhibits prostate cancer growth." in: Cancer letters, Vol. 349, Issue 1, pp. 15-25, (2014) (PubMed).
: "ATP-citrate lyase is essential for macrophage inflammatory response." in: Biochemical and biophysical research communications, Vol. 440, Issue 1, pp. 105-11, (2013) (PubMed).
: "ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells." in: The Journal of biological chemistry, Vol. 285, Issue 42, pp. 32606-15, (2010) (PubMed).
: "Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 10, pp. 2282-95, (2010) (PubMed).
Synonyme und alternative Namen zu ACLY
ATP citrate lyase (ACLY), ATP citrate lyase S homeolog (acly.S), ATP-citrate synthase (LOC587157), ATP citrate lyase (acly), ATP citrate lyase (ATPCL), ATP-citrate synthase (LOC5564509), citrate synthase, mitochondrial (CpipJ_CPIJ010291), ATP-citrate synthase (Bm1_26245), atp-citrate synthase (ACL), ATP citrate lyase (Acly), ATP citrate lyase a (aclya), A730098H14Rik, ACL, ACLY, acly, anon-WO0140519.179, ATPCL, AW538652, BcDNA:LD21334, cb722, CG8322, CLATP, Clatp, dATPCL, DDBDRAFT_0205389, DDBDRAFT_0235360, DDB_0205389, DDB_0235360, DmATPCL, Dmel\\CG8322, l(2)01466, l(2)k09217, n(2)k09217, zgc:92008Bezeichner auf Proteinebene für ACLY
- ATP citrate lyase
- ATP citrate synthase
- ATP-citrate synthase-like
- ATP-citrate lyase
- ATPCL-PD
- ATPCL-PE
- ATPCL-PF
- CG8322-PD
- CG8322-PE
- CG8322-PF
- ATP-citrate synthase
- citrate synthase, mitochondrial
- atp-citrate synthase
- ATP-citrate (pro-S-)-lyase
- citrate cleavage enzyme
Haben Sie etwas anderes gesucht?
- ACIN1
- Acid Phosphatase
- Acid Invertase
- AChR Ab
- ACHB3
- Achaete-scute complex protein T5
- Achaete-Scute Complex Homolog 1 (Drosophila)
- Achaete
- Acetylcholinesterase
- Acetylcholine
- Acetylated Lysine
- Acetyl-CoA Carboxylase beta
- Acetyl-CoA Carboxylase alpha
- Acetyl-CoA Carboxylase
- Acetyl-CoA
- Acetoin Reductase
- Acetate Kinase
- ACER3
- ACER2
- ACER1
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