ACE2 Proteine
(Angiotensin I Converting Enzyme 2 (ACE2))
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008].
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ACE2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
SDS, Func
1 reference
ACE2
Spezies: Paguma larvata
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
SDS
ACE2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
ACE2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
ACE2
Spezies: Cynomolgus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
ACE2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
ACE2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
ACE2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE
ACE2
Spezies: Rhesusaffen
Wirt: Human Cells
Recombinant
>95 % as determined by reducing SDS-PAGE.
Active
ACE2
Spezies: Rhesusaffen
Wirt: Human Cells
Recombinant
>95 % as determined by reducing SDS-PAGE.
Active
ACE2
Spezies: Cynomolgus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
ACE2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
SDS, Func
Active
ACE2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ELISA
ACE2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
ACE2
Spezies: Cynomolgus
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
SDS, ELISA
ACE2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
2 Referenzen
ACE2
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Func
Active
1 reference
ACE2
Spezies: Ratte
Wirt: Baculovirus infected Insect Cells
Recombinant
> 95 % by SDS - PAGE
SDS
1 image
ACE2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
SDS, Func
Active
1 image
ACE2
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
> 97 % as determined by SDS-PAGE
Active
1 image
Aktuelle Publikationen für unsere ACE2 Proteine
: "SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination." in: Advanced materials (Deerfield Beach, Fla.), Vol. 32, Issue 50, pp. e2005637, (2021) (PubMed).: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." in: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).
: "Dromedary camels as a natural source of neutralizing nanobodies against SARS-CoV-2." in: JCI insight, (2021) (PubMed).
: "SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity." in: Nature communications, Vol. 12, Issue 1, pp. 848, (2021) (PubMed).
: "Chicken Egg Yolk Antibodies (IgYs) block the binding of multiple SARS-CoV-2 spike protein variants to human ACE2." in: International immunopharmacology, Vol. 90, pp. 107172, (2021) (PubMed).
: "Neutralizing antibodies targeting the SARS-CoV-2 receptor binding domain isolated from a naïve human antibody library." in: Protein science : a publication of the Protein Society, Vol. 30, Issue 4, pp. 716-727, (2021) (PubMed).
: "A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency." in: Antiviral research, Vol. 194, pp. 105147, (2021) (PubMed).
: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)
: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).
: "Development of cell-based pseudovirus entry assay to identify potential viral entry inhibitors and neutralizing antibodies against SARS-CoV-2." in: Genes & diseases, (2020) (PubMed).
Aliase für ACE2 Proteine
angiotensin I converting enzyme (ACE) Proteineangiotensin I converting enzyme 2 (ACE2) Proteine
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (Ace2) Proteine
angiotensin I converting enzyme 2 (Ace2) Proteine
angiotensin I converting enzyme 2 (ace2) Proteine
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2) Proteine
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