rho GTPase Activating Protein 26 Proteine (ARHGAP26)

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. Zusätzlich bieten wir Ihnen GRAF Antikörper (90) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ARHGAP26 23092 Q9UNA1
ARHGAP26 71302 Q6ZQ82
Ratte ARHGAP26 ARHGAP26 307459  
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Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$12,127.90
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$12,127.90
Details
Wheat germ Human GST tag   10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$860.20
Details

ARHGAP26 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Am meisten referenzierte GRAF Proteine

  1. Human GRAF Protein expressed in Wheat germ - ABIN1345506 : Jarius, Scharf, Begemann, Stöcker, Probst, Serysheva, Nagel, Graus, Psimaras, Wildemann, Komorowski: Antibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in cerebellar ataxia. in Journal of neuroinflammation 2015 (PubMed)
    Show all 2 Pubmed References

Weitere Proteine zu rho GTPase Activating Protein 26 (ARHGAP26) Interaktionspartnern

Human rho GTPase Activating Protein 26 (ARHGAP26) Interaktionspartner

  1. We conclude that a transient interaction between Cdc42 (zeige CDC42 Proteine) and GRAF1 drives endocytic turnover and controls the transition essential for endosomal maturation of plasma membrane internalised by this mechanism.

  2. GRAF expression is a favorable prognostic marker in patients with acute myeloid leukemia (zeige BCL11A Proteine).

  3. ADAR1 (zeige ADAR Proteine) regulates the expression of ARHGAP26 through A-to-I RNA editing by disrupting the binding of miR (zeige MLXIP Proteine)-30b-3p and miR (zeige MLXIP Proteine)-573 within the 3' UTR of ARHGAP26.

  4. proposed that GRAF1 remodels membrane microdomains at adhesion sites into endocytic carriers, facilitating membrane turnover during cell morphological changes

  5. Findings suggest that the hypermethylation of GRAF promoter might be one of early events in the development of AML (zeige RUNX1 Proteine).

  6. a GTPase-activating protein (zeige RASA1 Proteine) that regulates muscle maturation and to highlight the functional importance of BAR domains in myotube formation

  7. Decreased level of GRAF transcript is associated with acute myeloid leukemia (zeige BCL11A Proteine), myelodysplastic syndrome and chronic myeloid leukemia (zeige BCL11A Proteine).

  8. The GRAF gene was down-regulated in AML (zeige RUNX1 Proteine), which might play a role in the leukemogenesis.

  9. The analysis of the expression pattern of the GRAF1/OPHN-1 (zeige OPHN1 Proteine)-L gene in human tissues and organs revealed the predominant brain expression of a novel splicing isoform.

  10. abnormal GRAF methylation might be an adverse prognostic event in MDS (zeige PAFAH1B1 Proteine)

GRAF (ARHGAP26) Protein Überblick

Protein Überblick

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit ARHGAP26

  • Rho GTPase activating protein 26 (ARHGAP26)
  • Rho GTPase activating protein 26 (Arhgap26)
  • 1810044B20Rik Protein
  • 2610010G17Rik Protein
  • 4933432P15Rik Protein
  • AI853435 Protein
  • ARHGAP26 Protein
  • GRAF Protein
  • GRAF1 Protein
  • mKIAA0621 Protein
  • OPHN1L Protein
  • OPHN1L1 Protein

Bezeichner auf Proteinebene für ARHGAP26

Rho GTPase activating protein 26 , rho GTPase-activating protein 26-like , GTPase regulator associated with focal adhesion kinase pp125(FAK) , oligophrenin-1-like protein , rho GTPase-activating protein 26 , rho-type GTPase-activating protein 26 , GTPase regulator associated with focal adhesion kinase , rhoGap protein

GENE ID SPEZIES
538219 Bos taurus
706084 Macaca mulatta
100393728 Callithrix jacchus
100436890 Pongo abelii
100484916 Ailuropoda melanoleuca
478046 Canis lupus familiaris
23092 Homo sapiens
71302 Mus musculus
307459 Rattus norvegicus
396113 Gallus gallus
Ausgewählte Anbieter für GRAF Proteine (ARHGAP26)
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