rho Family GTPase 3 Proteine (RND3)

RND3 encodes a protein which is a member of the small GTPase protein superfamily. Zusätzlich bieten wir Ihnen RND3 Antikörper (54) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RND3 390 P61587
RND3 74194 P61588
RND3 295588 Q6SA80
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Showing 10 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Orang-Utan His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Escherichia coli (E. coli) Human His tag   1 mg Anmelden zum Anzeigen 2 bis 3 Tage
Human Unkonjugiert   1 mg Anmelden zum Anzeigen 6 Days

RND3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Am meisten referenzierte RND3 Proteine

  1. Human RND3 Protein expressed in HEK-293 Cells - ABIN2731005 : Breslin, Daines, Doggett, Kurtz, Souza-Smith, Zhang, Wu, Yuan: Rnd3 as a Novel Target to Ameliorate Microvascular Leakage. in Journal of the American Heart Association 2016 (PubMed)

Weitere Proteine zu rho Family GTPase 3 (RND3) Interaktionspartnern

Human rho Family GTPase 3 (RND3) Interaktionspartner

  1. miR200b and miR200c targeted the expression of RhoE and inhibited the malignancy of nonsmall cell lung cancer (NSCLC) cells, and the downregulation of miR200b and miR200c may contribute to the high expression of RhoE in NSCLC.

  2. TUG1 can epigenetically inhibit the level of RND3 through binding to EZH2, thus promoting pre-eclampsia development.

  3. RND3 promotes Snail 1 protein degradation in glioblastoma tumor cells, promoting cell migration and neoplasm invasiveness.

  4. RhoE and ROCK2 regulate chemoresistance in hepatocellular carcinoma.

  5. This study Gene-based tests suggest evidence of association with related genes, ZEB2, RND3, MCTP1, CTBP2, and beta EEG.

  6. plexin-B2 is a downstream target for Rnd3, which contributes to its cellular function.

  7. Studies provide evidence that Rnd3 plays a dual role in cells; on one hand, it regulates cell proliferation, on the other hand, Rnd3 plays an important role in regulating metastasis and invasion. [review]

  8. Our data supported that RhoE could inhibit cell proliferation and promote apoptosis. Moreover, these tumor-suppressing effects might be acted through the negative regulation of EGFR/ERK signaling.

  9. constant degradation of RND3 by chaperone-mediated autophagy is required to sustain rapid proliferation of gastric cancer cells.

  10. RhoA-ROCK-Rnd3 feedback loop determined the local reassembly sites of the actin cortex during membrane blebbing.

  11. We conclude that downregulation of RND3 is responsible for the enhancement of Notch activity that promotes glioblastoma genesis.

  12. the development and application of a novel data integration methodology reveals novel functions of RND3 in controlling glioma cell migration, invasion, proliferation, angiogenesis and clinical outcome.

  13. Rnd3 regulates lung cancer cell proliferation through notch signaling.

  14. CXCR4 might be a downstream effector for RhoE

  15. Transfection of pre-miR-200c reduces RhoE expression.

  16. RhoE may participate in human cancer progression and act as a candidate target of p53, and these findings also strongly suggest that RhoE may be a new candidate tumor suppressor and could serve as a potential target in the gene therapy of cancer.

  17. define RhoE as a Notch1 target that is essential for recruitment of N1IC to promoters of Notch1 target genes, establishing a regulatory feedback loop in Notch1 signaling

  18. MicroRNA-200b acts as a stimulant for the proliferation of HTFs by targeting p27/kip1 and RND3.

  19. a mechanism according to which proteasomal degradation of RhoE by Skp2 regulates its protein levels to control cellular proliferation.

  20. alteration of the malignant behavior of cancer cells by AES is related to RND3 regulation.

Mouse (Murine) rho Family GTPase 3 (RND3) Interaktionspartner

  1. Rnd3 acted as a novel proangiogenic factor involved in cardiac responsive angiogenesis through HIF1alpha-VEGFA signaling promotion.

  2. These results indicate that RhoE plays a role in suppressing tumor initiation and progression.

  3. Rnd3 is a novel factor involved in intracellular calcium homeostasis regulation in the heart.

  4. Animals with Rnd3 haploinsufficiency are predisposed to hemodynamic stress. Hyperactivation of Rho kinase activity is responsible in part for the apoptotic cardiomyopathy development.

  5. Data show that the Plexin B2 receptor interacts physically and functionally with Rnd3 and stimulates RhoA activity in migrating cortical neurons.

  6. RhoE is indispensable for osteoclast migration and bone resorption by maintaining fast actin turnover in podosomes. RhoE activates podosome component cofilin by inhibiting its Rock-mediated phosphorylation.

  7. although Rnd3 expression is controlled transcriptionally by Ascl1, this proneural factor is itself required in radial glial progenitors only for proper orientation of cell divisions

  8. Rnd3 is a regulator of Notch1 signaling

  9. These findings support our previous report revealing the important role of RhoE in the normal development of the nervous system

  10. the important role of Rnd3/RhoE in the normal development

  11. a well defined Rnd3 effector Syx

  12. RhoE induces stress fiber disassembly by directly binding ROCK I and inhibiting it from phosphorylating downstream targets

  13. RhoE inhibits cell cycle progression upstream of the pRb checkpoint.

  14. study shows RhoE physiological upregulation before myoblast fusion is responsible for the decrease in RhoA and ROCKI activities, which are required for the fusion process; therefore, we conclude that RhoE is an essential regulator of myoblast fusion

  15. Our results suggest that RhoE can play important roles in the postnatal development and maturation of the CNS, especially in the migratory processes affecting the neurones.

  16. RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation.

RND3 Protein Überblick

Protein Überblick

This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Genbezeichner und Symbole assoziert mit rho Family GTPase 3 Proteine (RND3)

  • Rho family GTPase 3 (RND3)
  • Rho family GTPase 3 L homeolog (rnd3.L)
  • Rho family GTPase 3 (Rnd3)
  • Rho family GTPase 3a (rnd3a)
  • 2610017M01Rik Protein
  • AI661404 Protein
  • arhe Protein
  • id:ibd2712 Protein
  • id:ibd2919 Protein
  • memB Protein
  • MGC83857 Protein
  • rho8 Protein
  • RHOE Protein
  • rnd3 Protein
  • wu:fc39h07 Protein
  • zgc:73080 Protein

Bezeichner auf Proteinebene für rho Family GTPase 3 Proteine (RND3)

protein MemB , ras homolog gene family, member E , rho-related GTP-binding protein Rho8 , rho-related GTP-binding protein RhoE , small GTP binding protein Rho8 , Rho family GTPase 3 , Rho related protein Rnd3/Rho8 , rho8 , fc39h07

390 Homo sapiens
424312 Gallus gallus
431945 Xenopus laevis
483917 Canis lupus familiaris
694168 Macaca mulatta
783333 Bos taurus
74194 Mus musculus
295588 Rattus norvegicus
397559 Sus scrofa
100172882 Pongo abelii
100725613 Cavia porcellus
80963 Danio rerio
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