phosphofructokinase, Platelet Proteine (PFKP)

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). Zusätzlich bieten wir Ihnen PFKP Antikörper (127) und PFKP Kits (41) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PFKP 5214 Q01813
PFKP 56421 Q9WUA3
PFKP 60416 P47860
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Top PFKP Proteine auf antikoerper-online.de

Showing 10 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$672.00
Details
Human Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$385.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
Details
Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human PFKP Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$625.39
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$4,313.83
Details
Escherichia coli (E. coli) Maus T7 tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$704.00
Details
Escherichia coli (E. coli) Ratte T7 tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$733.00
Details

PFKP Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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Weitere Proteine zu phosphofructokinase, Platelet (PFKP) Interaktionspartnern

Human phosphofructokinase, Platelet (PFKP) Interaktionspartner

  1. Snail functions as a metabolic switch between aerobic glycolysis and pentose phosphate pathway by repressing PFKP, a cancer-specific PFK-1, allowing cancer cell survival under metabolic stress.

  2. Here the authors show that PFK1 (zeige PFKM Proteine) platelet isoform is upregulated in Glioblastoma and is required for tumor growth mechanistically, such upregulation is due to an increased stability induced by AKT (zeige AKT1 Proteine) activation via phosphorylation on residue S386.

  3. Data indicate that platelet isoform of phosphofructokinase (PFKP) not only is required for metabolic reprogramming and maintaining cell proliferation, but also may be a valid target for anti-renal cancer pharmaceutical agents.

  4. The crystallized PFKP is permanently activated by a deletion of the 22 C-terminal residues.

  5. Anti-human protein S antibody induces tissue factor expression through a direct interaction with PFKP and ERK1/2 activation in coronary artery endothelial cells.

  6. expression of TARDBP (zeige TARDBP Proteine) is significantly elevated in HCC (zeige FAM126A Proteine) and it regulates the expression of PFKP, the rate-limiting enzyme for glycolysis, through negative regulation of microRNA 520s (miR (zeige MLXIP Proteine)-520s).

  7. KLF4 (zeige KLF4 Proteine) plays a role in maintenance of high glycolytic metabolism by transcriptional activation of the PFKP gene in breast cancer cells.

  8. PFKP was identified using a trifunctional phenyl sulfonate probe.

  9. Two phosphofructokinase (PFK) chimeras were constructed by exchanging the N- and C-terminal halves of the mammalian M- and C-type isozymes.

  10. PFKP polymorphisms play no apparent role in the development of common forms of obesity in the Danish population.

PFKP Protein Überblick

Protein Überblick

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM\; MIM 610681) and liver (PFKL\; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981)

Genbezeichner und Symbole assoziert mit PFKP

  • phosphofructokinase, platelet (pfkp)
  • phosphofructokinase, platelet (PFKP)
  • phosphofructokinase, platelet S homeolog (pfkp.S)
  • ATP-dependent 6-phosphofructokinase, platelet type (LOC100549777)
  • phosphofructokinase, platelet (Pfkp)
  • 1200015H23Rik Protein
  • 9330125N24Rik Protein
  • pfk Protein
  • PFK-C Protein
  • PFKF Protein
  • PFKM Protein
  • PFKP Protein

Bezeichner auf Proteinebene für PFKP

phosphofructokinase, platelet , 6-phosphofructokinase type C , PFK-C , phosphofructo-1-kinase isozyme C , phosphofructokinase 1 , phosphohexokinase , 6-phosphofructokinase, platelet type , Phosphofructokinase, platelet type , ATP:D-fructose 6-phosphate 1-phosphotransferase , 6-phosphofructo-1-kinase, C-type , phosphofructokinase C isozyme , phosphofructokinase, muscle

GENE ID SPEZIES
394825 Xenopus (Silurana) tropicalis
450266 Pan troglodytes
100022041 Monodelphis domestica
100037146 Xenopus laevis
100070818 Equus caballus
100173619 Pongo abelii
100229947 Taeniopygia guttata
100549777 Meleagris gallopavo
100561110 Anolis carolinensis
100601116 Nomascus leucogenys
5214 Homo sapiens
56421 Mus musculus
60416 Rattus norvegicus
100009526 Oryctolagus cuniculus
100722738 Cavia porcellus
100521394 Sus scrofa
478019 Canis lupus familiaris
507119 Bos taurus
428411 Gallus gallus
101108592 Ovis aries
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